Ghiasian Leila, Abdolalizadeh Parya, Hadavandkhani Ali, Eshaghi Acieh, Hadi Yasaman, Nadjafi-Semnani Fatemeh
Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Department of Ophthalmology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2022 Jul 26;34(2):200-207. doi: 10.4103/joco.joco_249_21. eCollection 2022 Apr-Jun.
To compare Pentacam indices in normal eyes with different corneal thicknesses.
It is a retrospective observational study. Ninety-six normal eyes of 96 patients who were referred for refractive surgery in a tertiary university-based hospital from October 2015 to April 2019 were recruited consecutively. Corneal keratometry as well as Pentacam's software Belin-Ambrósio Enhanced Ectasia Display (BAD) parameters including pachymetry progression indices (PPIs), maximum Ambrosio's relational thickness (ART-max), corneal elevations, normalized deviations, BAD total deviation value (BAD-D), and anterior surface indices were measured by Pentacam HR (Type 70900). The included were classified as thin (26 eyes), average (45 eyes), and thick (25 eyes) corneas with the thinnest point thickness of ≤496 μm, 497-595 μm, and ≥596 μm, respectively. The specificities of all parameters were calculated based on routine cut-off values.
The refraction, keratometry, and elevations were not different ( > 0.05). All PPIs (minimum, average, and maximum) of thick corneas were significantly lower than average and thin corneas ( < 0.001). ART-max increased by thickening of the cornea ( < 0.001). BAD-D score and normalized indices of pachymetric parameters decreased with the increase of thickness ( < 0.001), while specificities of all indices increased with corneal thickening. More than 96% of thick corneas were classified as normal PPI-max (24/25), ART-max (25/25), and BAD-D (25/25), while nearly <54% of thin corneas (14/26 for PPI-max, 9/26 for ART-max, and 12/26 for BAD-D) were normal.
The pachymetry-related indices and BAD-D were different among normal corneas with various thicknesses. The specificities of PPIs, ART-max, and BAD-D of thin corneas were lower than in thick corneas.
比较不同角膜厚度的正常眼的Pentacam测量指标。
这是一项回顾性观察研究。连续纳入了2015年10月至2019年4月期间在一所大学附属医院接受屈光手术评估的96例患者的96只正常眼。使用Pentacam HR（70900型）测量角膜曲率以及Pentacam软件的贝林-安布罗西奥增强型扩张显示（BAD）参数，包括测厚进展指数（PPI）、最大安布罗西奥相关厚度（ART-max）、角膜高度、标准化偏差、BAD总偏差值（BAD-D）和前表面指数。根据最薄点厚度将纳入者分为薄角膜（26只眼）、平均角膜（45只眼）和厚角膜（25只眼），最薄点厚度分别≤496μm、497 - 595μm和≥596μm。基于常规临界值计算所有参数的特异性。
屈光、角膜曲率和高度无差异（>0.05）。厚角膜的所有PPI（最小、平均和最大）均显著低于平均角膜和薄角膜（<0.001）。ART-max随角膜增厚而增加（<0.001）。BAD-D评分和测厚参数的标准化指数随厚度增加而降低（<0.001），而所有指数的特异性随角膜增厚而增加。超过96%的厚角膜在PPI-max（24/25）、ART-max（25/25）和BAD-D（25/25）方面被分类为正常，而薄角膜中近<54%（PPI-max为14/26，ART-max为9/26，BAD-D为12/26）为正常。
不同厚度的正常角膜在测厚相关指标和BAD-D方面存在差异。薄角膜的PPI、ART-max和BAD-D的特异性低于厚角膜。
