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视网膜星形胶质细胞:它们局限于哺乳动物视网膜的血管化部分。

Retinal astrocytes: their restriction to vascularized parts of the mammalian retina.

作者信息

Schnitzer J

出版信息

Neurosci Lett. 1987 Jul 9;78(1):29-34. doi: 10.1016/0304-3940(87)90556-8.

DOI:10.1016/0304-3940(87)90556-8
PMID:3614770
Abstract

The distribution of astrocytes has been studied in whole-mounted horse and monkey retinae by the immunocytochemical localization of glial fibrillary acidic protein (GFAP). In the horse, astrocytes were found to be restricted to a narrow zone close to the optic nerve head. This is also the only region of the horse retina that is vascularized. In the monkey, astrocytes were found ubiquitously in the nerve fiber layer of the retina, apart from the avascular fovea centralis which lacked astrocytes. These observations strongly suggest that retinal astrocytes co-occur with blood vessels, a feature which may be common among mammals.

摘要

通过胶质纤维酸性蛋白(GFAP)的免疫细胞化学定位,已对马和猴的整个视网膜中星形胶质细胞的分布进行了研究。在马中,发现星形胶质细胞局限于靠近视神经乳头的一个狭窄区域。这也是马视网膜中唯一有血管分布的区域。在猴中,除了缺乏星形胶质细胞的无血管中央凹外,在视网膜的神经纤维层中普遍发现有星形胶质细胞。这些观察结果有力地表明,视网膜星形胶质细胞与血管同时存在,这一特征在哺乳动物中可能很常见。

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