Liu Zi-Bo, Liu Yan-Song, Zhao Long, Li Man-Yu, Liu Chun-Hui, Zhang Chun-Xia, Li Hong-Ling
Department of Endocrinology, Second Hospital of Hebei Medical University, Shijiazhuang, China.
The Second Department of Rehabilitation, Second Hospital of Hebei Medical University, Shijiazhuang, China.
Front Psychol. 2022 Sep 6;13:947861. doi: 10.3389/fpsyg.2022.947861. eCollection 2022.
To investigate the short-term effect of music therapy combined with binaural frequency difference therapy on patients with consciousness disorder.
Ninety patients with definite diagnosis of disorders of consciousness (DOC) were selected. These patients were randomly divided into control group, experiment 1 group and experiment 2 group, with 30 patients in each group. The control group was treated with routine clinical treatment and rehabilitation. In experiment 1 group, music therapy was added to the control group. In experimental group 2, music therapy combined with binaural α frequency difference therapy was added to the control group. All patients were assessed before and after 30 treatments. The assessment items included Glasgow Coma Scale (GCS), Coma Recovery Scale revised (CRS-R), electroencephalogram (EEG), upper somatosensory evoked potential (USEP), and brainstem auditory evoked potential (BAEP).
Before treatment, there were no significant differences in GCS score, CRS-R score, USEP, BAEP, and EEG scores among the three groups ( > 0.05). After 30 times of treatment, GCS score, CRS-R score, USEP, BAEP, and EEG scores in 3 groups were significantly higher than those before treatment ( < 0.05), and experimental group 2 >experimental group 1 >control group ( < 0.05). And the consciousness rate of experimental group 2 was better than experimental group 1, experimental group 1 was better than the control group and the difference was statistically significant ( < 0.05).
Music therapy combined with binaural α frequency difference therapy is more effective in stimulating DOC patients.
探讨音乐疗法联合双耳频率差疗法对意识障碍患者的短期疗效。
选取90例确诊为意识障碍（DOC）的患者。将这些患者随机分为对照组、实验1组和实验2组，每组30例。对照组采用常规临床治疗和康复治疗。实验1组在对照组治疗基础上加用音乐疗法。实验2组在对照组治疗基础上加用音乐疗法联合双耳α频率差疗法。所有患者在治疗30次前后进行评估。评估项目包括格拉斯哥昏迷量表（GCS）、修订版昏迷恢复量表（CRS-R）、脑电图（EEG）、上肢体感诱发电位（USEP）和脑干听觉诱发电位（BAEP）。
治疗前，三组患者的GCS评分、CRS-R评分、USEP、BAEP及EEG评分比较，差异均无统计学意义（>0.05）。治疗30次后，三组患者的GCS评分、CRS-R评分、USEP、BAEP及EEG评分均显著高于治疗前（<0.05），且实验2组>实验1组>对照组（<0.05）。实验2组的意识恢复率优于实验1组，实验1组优于对照组，差异有统计学意义（<0.05）。
音乐疗法联合双耳α频率差疗法对刺激DOC患者更有效。
