在意大利第一波新冠疫情期间，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染对结核病结局及随访的影响：一项全国性在线调查
Impact of SARS-CoV-2 infection on tuberculosis outcome and follow-up in Italy during the first COVID-19 pandemic wave: a nationwide online survey.
作者信息
Canetti Diana, Antonello Roberta Maria, Saderi Laura, Giro Mara, Goletti Delia, Sarmati Loredana, Rodari Paola, Bocchino Marialuisa, Schirò Miriam, Riccardi Niccolò, Sotgiu Giovanni
机构信息
StopTB Italia Onlus, Milan, Italy.
Department of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
出版信息
Infez Med. 2022 Sep 1;30(3):418-426. doi: 10.53854/liim-3003-10. eCollection 2022.
Abstract
BACKGROUND
SARS-CoV-2 pandemic affected tuberculosis (TB) management. This Italian nationwide survey assessed COVID-19 impact on TB care and outcomes.
MATERIALS AND METHODS
Twenty-one hospitals or referral centres fulfilled an online survey. Primary objective was to describe clinical features, outcomes and retention in care in subjects with latent TB infection (LTBI) or disease over the first wave of COVID-19 pandemic. Secondary objectives were the assessment of risk factors, co-morbidities, diagnostics, radiological findings, and outcomes of COVID-19 in the study population.
RESULTS
254 patients with LTBI or active TB were included. In co-infected (SARS-CoV-2, LTBI/TB) patients, recovery occurred in 29/32 (90.6%) cases, death in one case. High retention in care was preserved.
CONCLUSION
in our cohort, outcomes did not seem to be adversely conditioned by incident COVID-19.
摘要
背景
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行影响了结核病（TB）的管理。这项意大利全国性调查评估了2019冠状病毒病（COVID-19）对结核病治疗及治疗结果的影响。
材料与方法
21家医院或转诊中心完成了一项在线调查。主要目的是描述在COVID-19大流行第一波期间，潜伏性结核感染（LTBI）或结核病患者的临床特征、治疗结果及治疗依从性。次要目的是评估研究人群中COVID-19的危险因素、合并症、诊断、影像学检查结果及治疗结果。
结果
纳入254例LTBI或活动性结核病患者。在合并感染（SARS-CoV-2、LTBI/TB）的患者中，29/32例（90.6%）康复，1例死亡。治疗依从性保持较高水平。
结论
在我们的队列中，COVID-19的发生似乎并未对治疗结果产生不利影响。
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