Menotti Giulia, Giglia Maddalena, Riccardi Niccolò, Diop Yacine Mar, Ndiaye Mamadou, Gning Lamin, Diaw Mama Moussa, Fumagalli Giovanni, Saderi Laura, Sotgiu Giovanni, Besozzi Giorgio, Tadolini Marina
Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.
StopTB Italia ODV, Milan, Italy.
Infez Med. 2025 Sep 1;33(3):321-328. doi: 10.53854/liim-3303-9. eCollection 2025.
The Coronavirus (COVID-19) pandemic significantly impacted on tuberculosis (TB) services (TB) services in both high and low TB burden countries. Objectives: This study aimed to investigate the impact of COVID-19 on TB outpatient services in terms of new TB case notifications and treatment outcomes in a rural area of Senegal.
A retrospective observational study was conducted at the Health Care Centre of Diofior (HCD) in the Fimela district, Fatick Region (Senegal), covering the period from January 1st, 2018, to December 31st, 2022. Data were divided into pre-COVID-19 (until March 31st, 2020) and during-COVID-19 (from April 1st, 2020) periods for analysis.
Among the 246 TB cases included (63.4% male, median age 38.4 years), 94 (38.2%) had been diagnosed in the pre-COVID-19 period and 152 (61.8%) in the during-COVID-19 period. In 2020, TB case notifications dropped by 24.4% compared to 2019, followed by an increase of 70.6% in 2021 and 91.2% in 2022. The TB treatment success rate decreased from 85.1% before COVID-19 to 77.6% in during-COVID-19 period. Moreover, mortality increased from 2.1% to 5.3%, and the lost-to-follow-up rate rose from 8.5% to 14.5% between the pre- and during-COVID-19 periods.
Although the number of COVID-19 cases reported in Senegal was relatively low in the study period compared to other settings, our study indicates that the pandemic had a significant impact on TB services in this rural area of Senegal.
冠状病毒病（COVID-19）大流行对高结核病负担国家和低结核病负担国家的结核病服务均产生了重大影响。目的：本研究旨在调查COVID-19对塞内加尔农村地区结核病门诊服务在新结核病病例报告和治疗结果方面的影响。
在塞内加尔法蒂克地区菲梅拉区的迪奥菲奥尔医疗中心（HCD）进行了一项回顾性观察研究，涵盖2018年1月1日至2022年12月31日期间。数据分为COVID-19之前（至2020年3月31日）和COVID-19期间（从2020年4月1日起）两个时期进行分析。
纳入的246例结核病病例中（63.4%为男性，中位年龄38.4岁），94例（38.2%）在COVID-19之前被诊断，152例（61.8%）在COVID-19期间被诊断。2020年，结核病病例报告数与2019年相比下降了24.4%，随后在2021年增加了70.6%，在2022年增加了91.2%。结核病治疗成功率从COVID-19之前的85.1%降至COVID-19期间的77.6%。此外，死亡率从2.1%升至5.3%，失访率在COVID-19之前和期间从8.5%升至14.5%。
尽管在研究期间塞内加尔报告的COVID-19病例数与其他地区相比相对较低，但我们的研究表明，该大流行对塞内加尔这个农村地区的结核病服务产生了重大影响。
