Sun A H, Xiao S Z, Li B S, Li Z J, Wang T Y, Zhang Y S
ORL J Otorhinolaryngol Relat Spec. 1987;49(3):118-22. doi: 10.1159/000275920.
Cochlear changes were studied in 141 growing rats raised on a basic iron-deficient diet for 7-100 days; 130 rats served as normal or chronic anemia controls. Electrophysiological findings showed that the incidence of an auditory threshold elevation of more than 15 dB was 31.85% in the iron-deficient rats, but it was unchanged in all the control animals. The main cochlear histopathological changes induced by iron deficiency were strial atrophy and reduction of spiral ganglion cells. It is concluded that the observed anomalies may be attributed solely to iron deficiency of the cochlear tissue.
对141只以缺铁基础饮食饲养7至100天的生长中大鼠的耳蜗变化进行了研究；130只大鼠作为正常或慢性贫血对照。电生理结果显示，缺铁大鼠中听觉阈值升高超过15 dB的发生率为31.85%，但所有对照动物中该发生率未发生变化。缺铁引起的主要耳蜗组织病理学变化是血管纹萎缩和螺旋神经节细胞减少。得出的结论是，观察到的异常可能仅归因于耳蜗组织的缺铁。
