Ferrillo Martina, Nucci Ludovica, Giudice Amerigo, Calafiore Dario, Marotta Nicola, Minervini Giuseppe, d'Apuzzo Fabrizia, Ammendolia Antonio, Perillo Letizia, de Sire Alessandro
Dentistry Unit, Department of Health Sciences, University of Catanzaro "Magna Graecia", Catanzaro, Italy.
Dentistry Unit, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Cranio. 2025 Mar;43(2):258-274. doi: 10.1080/08869634.2022.2126079. Epub 2022 Sep 23.
The aim of this systematic review with meta-analysis was to evaluate the efficacy of conservative interventions in pain relief in patients with intracapsular temporomandibular disorders (TMD).
PubMed, Scopus, and Web of Science were systematically searched until January 1, 2022 to identify randomized controlled trials (RCTs) presenting patients with diagnosis of intracapsular TMD according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD), conservative approaches as interventions, and pain intensity as outcome.
Out of 3372 papers, 13 RCTs were included, with 844 study participants. Most of them (n = 7) investigated the efficacy of splint appliance. Meta-analysis revealed that rehabilitative interventions had a significant overall effect size of 0.75 [0.17, 1.34], reporting splint appliance and laser therapy as significantly effective treatments.
Findings of this systematic review with network meta-analysis suggested that conservative approaches might be effective in pain relief of intracapsular TMD patients.
本项带有荟萃分析的系统评价旨在评估保守干预措施对囊内颞下颌关节紊乱病(TMD)患者疼痛缓解的疗效。
对PubMed、Scopus和Web of Science进行系统检索,直至2022年1月1日,以识别根据颞下颌关节紊乱病诊断标准(DC/TMD)诊断为囊内TMD的患者、采用保守方法作为干预措施以及以疼痛强度作为结局指标的随机对照试验(RCT)。
在3372篇论文中,纳入了13项RCT,共有844名研究参与者。其中大多数研究(n = 7)调查了咬合板矫治器的疗效。荟萃分析显示,康复干预的总体效应量显著为0.75 [0.17, 1.34],表明咬合板矫治器和激光治疗是显著有效的治疗方法。
本项带有网状荟萃分析的系统评价结果表明,保守方法可能对囊内TMD患者的疼痛缓解有效。