Wang Liujing, Zhang Yanni, Chen Haiyan, Jin Chenxi, Shen Wei, Li Ziyuan, Zhang Wei, Shi Yuxin, Hou Yiyang, Li Xiaoxuan, Guo Jing
Department of Stomatology, Ningbo Municipal Hospital of Traditional Chinese Medicine (TCM) Affiliated Hospital of Zhejiang Chinese Medical University, Ningbo Zhejiang, 315010, China.
Ningbo Stomatology Hospital, Ningbo, Zhejiang, 315010, China.
BMC Oral Health. 2025 Jul 28;25(1):1267. doi: 10.1186/s12903-025-06379-3.
This systematic review and meta-analysis aimed to evaluate the effectiveness of anterior repositioning splint (ARS) compared with other conservative treatments for temporomandibular joint (TMJ) disc displacement.
This systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. Four databases (PubMed, Web of Science, Embase, and Cochrane) were searched up to January 8, 2024, so as to identify eligible randomized controlled trials (RCTs) of ARS for the treatment of TMJ disc displacement.
This analysis finally included 14 studies. The research findings showed that after 3 months of treatment, ARS significantly improved VAS score compared to the physical therapy [MD: -1.90, 95%CI (-2.69, -1.11), P < 0.00001] and behavioral therapy [MD=-3.00, 95%CI (-4.30, -1.71), P < 0.05]. However, it was less effective than other occlusal splint treatments [MD: 0.71, 95%CI (0.30, 1.11), P = 0.0007]. In terms of pain free mouth opening, ARS significantly outperformed the physical therapy [MD = 2.83, 95%CI (1.04, 4.62), P = 0.002] and behavioral therapy [MD: 1.79, 95%CI (1.33, 2.26), P < 0.00001] after 3 months of treatment. No significant difference was observed between ARS and other occlusal splint treatments [MD=-0.97, 95%CI (-2.65, 0.71), P = 0.26]. Regarding maximal active mouth opening, after 3 months of treatment, ARS was significantly superior to the physical therapy [MD = 3.10, 95%CI (1.05, 5.15), P = 0.03] and behavioral therapy [MD: 3.19, 95%CI (2.71, 3.66), P < 0.00001]. There was no significant difference between ARS and other occlusal splint treatments [MD: - 1.92, 95%CI (-4.05, 0.21), P = 0.08]. In terms of maximal passive mouth opening, ARS was significantly more effective than physical therapy [MD: 1.91, 95%CI (0.13, 3.68), P = 0.04]. There was no significant difference between ARS and other occlusal splint treatments [MD: -2.25, 95%CI (-5.02, 0.53), P = 0.11]. For relieving jaw popping symptoms, ARS was significantly more effective than the physical therapy [RR:0.45, 95%CI (0.34, 0.58), P < 0.00001] and behavioral therapy [RR: 0.48, 95%CI (0.36, 0.64), P < 0.00001]. However, no significant difference was found between ARS and other occlusal splint treatments [RR: 1.29, 95%CI (0.83, 2.02), P = 0.26].
A total of 14 studies were included in this systematic review and meta-analysis, which compared the efficacy of ARS with other conservative treatments for disc displacement. While ARS did not demonstrate a significant difference compared to physical therapy in improving TMJ pain, popping, and mandibular motor function in the initial treatment phase, it exhibited more pronounced effects than physical therapy and behavioral therapy with continued use. Splints have demonstrated significant efficacy in alleviating TMJ popping and improving mandibular movement. However, ARS has not shown superior effectiveness compared to other types of occlusal splints in alleviating pain.
本系统评价和荟萃分析旨在评估前牙复位夹板(ARS)与其他保守治疗方法相比,对颞下颌关节(TMJ)盘移位的治疗效果。
本系统评价和荟萃分析按照PRISMA指南进行。检索了四个数据库(PubMed、Web of Science、Embase和Cochrane),截至2024年1月8日,以确定符合条件的关于ARS治疗TMJ盘移位的随机对照试验(RCT)。
本分析最终纳入14项研究。研究结果表明,治疗3个月后,与物理治疗相比,ARS显著改善了视觉模拟评分(VAS)[平均差(MD):-1.90,95%置信区间(CI)(-2.69,-1.11),P < 0.00001]和行为治疗[MD = -3.00,95%CI(-4.30,-1.71),P < 0.05]。然而,它的效果不如其他咬合夹板治疗[MD:0.71,95%CI(0.30,1.11),P = 0.0007]。在无痛开口方面,治疗3个月后,ARS明显优于物理治疗[MD = 2.83,95%CI(1.04,4.62),P = 0.002]和行为治疗[MD:1.79,95%CI(1.33,2.26),P < 0.00001]。ARS与其他咬合夹板治疗之间未观察到显著差异[MD = -0.97,95%CI(-2.65,0.71),P = 0.26]。关于最大主动开口度,治疗3个月后,ARS明显优于物理治疗[MD = 3.10,95%CI(1.05,5.15),P = 0.03]和行为治疗[MD:3.19,95%CI(2.71,3.66),P < 0.00001]。ARS与其他咬合夹板治疗之间无显著差异[MD:-1.92,95%CI(-4.05,0.21),P = 0.08]。在最大被动开口度方面,ARS比物理治疗明显更有效[MD:1.91,95%CI(0.13,3.68),P = 0.04]。ARS与其他咬合夹板治疗之间无显著差异[MD:-2.25,95%CI(-5.02,0.53),P = 0.11]。对于缓解关节弹响症状而言(缓解关节弹响症状,ARS比物理治疗[相对危险度(RR):0.45,95%CI(0.34,0.58),P < 0.000(01)]和行为治疗[RR:0.48,95%CI(0.36,0.64),P < 0.000(01)]明显更有效。然而,ARS与其他咬合夹板治疗之间未发现显著差异[RR:1.29,95%CI(0.83,2.02),P = 0.26]。
本系统评价和荟萃分析共纳入14项研究,比较了ARS与其他保守治疗方法对盘移位的疗效。虽然在初始治疗阶段,ARS与物理治疗相比,在改善TMJ疼痛、弹响和下颌运动功能方面未显示出显著差异,但持续使用时,它比物理治疗和行为治疗表现出更明显的效果。夹板在缓解TMJ弹响和改善下颌运动方面已显示出显著疗效。然而,在缓解疼痛方面,ARS与其他类型的咬合夹板相比并未显示出更优的效果。