Department of Pathology, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India.
Department of Surgery, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, India.
J Cancer Res Ther. 2022 Jul-Sep;18(4):1186-1188. doi: 10.4103/jcrt.JCRT_107_19.
Primary leiomyosarcoma kidney is a rare tumor with an aggressive nature. Leiomyosarcoma is one of the common histologic types of the sarcomas, comprising 60% of all sarcomas. Sarcomatoid renal cell carcinoma is a close differential of renal leiomyosarcoma as both tumors have spindle-shaped cells. The former has a more pleomorphic character with nuclear grade four, which can be differentiated on the basis of immunohistochemistry. Hence, the diagnosis of primary renal leiomyosarcoma poses a diagnostic challenge. One such case of renal leiomyosarcoma in a 45-year-old male is being discussed here.
原发性肾平滑肌肉瘤是一种罕见的具有侵袭性的肿瘤。平滑肌肉瘤是肉瘤的常见组织学类型之一,占所有肉瘤的 60%。肉瘤样肾细胞癌是肾平滑肌肉瘤的密切鉴别诊断,因为这两种肿瘤都有梭形细胞。前者具有更多的多形性特征,核分级为四级,可基于免疫组织化学进行区分。因此,原发性肾平滑肌肉瘤的诊断具有挑战性。本文讨论了一例 45 岁男性的肾平滑肌肉瘤病例。