Lindgren Stefan, Hjortswang Henrik, Moum Björn, Vasko Peter, H Lund Lars
professor, överläkare, sektionen för gastroenterologi, Skånes universitetssjukhus Malmö.
docent, överläkare, mag-tarmmedicinska kliniken, Universitetssjukhuset i Linköping.
Lakartidningen. 2022 Sep 21;119:22014.
Iron deficiency, defined as ferritin <100 µg/L or ferritin 100-299 µg/L if the transferrin saturation is <20 %, with or without anaemia is a common comorbidity in patients with acute and chronic heart failure. International and Swedish guidelines recommend treatment of iron deficiency with intravenous iron in patients with symptomatic heart failure and ejection fraction <50 %. Controlled studies document positive effects from treatment with iron carboxymaltose on symptoms, quality of life, functional parameters and risk of hospitalisation. We present a simple algoritm based on published data to help the responsible physician to manage these patients in clinical practice.
缺铁（定义为血清铁蛋白<100μg/L，或转铁蛋白饱和度<20%时血清铁蛋白为100 - 299μg/L，无论有无贫血）是急慢性心力衰竭患者常见的合并症。国际和瑞典指南推荐，对于症状性心力衰竭且射血分数<50%的患者，采用静脉注射铁剂治疗缺铁。对照研究证明，使用羧基麦芽糖铁治疗对症状、生活质量、功能参数和住院风险有积极影响。我们根据已发表的数据提出一种简单的算法，以帮助负责的医生在临床实践中管理这些患者。
