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对于在卵胞浆内单精子注射(ICSI)周期中接受控制性卵巢过度刺激的女性,宫腔镜息肉切除术是否需要取消周期?

Does hysteroscopic resection of polyps require cycle cancellation in women undergoing controlled ovarian hyperstimulation in the ICSI cycle?

作者信息

Oral Serkan

机构信息

Haliç University Faculty of Medicine, Department of Obstetrics and Gynecology, İstanbul, Turkey.

出版信息

Turk J Obstet Gynecol. 2022 Sep 23;19(3):201-206. doi: 10.4274/tjod.galenos.2022.79363.

Abstract

OBJECTIVE

Endometrial polyps are one of the most extensive pathologies in the uterus and can be detected incidentally during assisted reproductive therapy in asymptomatic women.

MATERIALS AND METHODS

In patients planned for in vitro fertilization or intracytoplasmic sperm injection (ICSI) treatment, embryo freezing, or cycle cancelation options are mandatory in many clinics when detected at the beginning of the cycle. In our study, in ICSI treatment, patients with a single endometrial polyp smaller than 1.5 cm, who underwent hysteroscopic polyp resection at the beginning of the cycle and underwent fresh embryo transfer without canceling the treatment (n=31), and patients with the same characteristics of endometrial polyp who underwent hysteroscopic polyp resection before the cycle (n=34) are compared within the pregnancy, abortion and live birth rates.

RESULTS

As a result, no statistical difference was found between the two groups' pregnancy, abortion, and live birth rates.

CONCLUSION

Hysteroscopic resection of polyps during ovarian stimulation in ICSI treatment does not affect pregnancy and live birth rates and may eliminate the necessity of freezing.

摘要

目的

子宫内膜息肉是子宫内最常见的病变之一,在无症状女性的辅助生殖治疗过程中可能会偶然被发现。

材料与方法

在计划进行体外受精或卵胞浆内单精子注射(ICSI)治疗、胚胎冷冻或周期取消的患者中,许多诊所规定,若在周期开始时检测到息肉,则这些选项是必须的。在我们的研究中,在ICSI治疗中,比较了在周期开始时接受宫腔镜息肉切除术且未取消治疗而进行新鲜胚胎移植的单个子宫内膜息肉小于1.5 cm的患者(n = 31),以及在周期前接受宫腔镜息肉切除术的具有相同子宫内膜息肉特征的患者(n = 34)的妊娠、流产和活产率。

结果

结果显示,两组的妊娠、流产和活产率之间未发现统计学差异。

结论

在ICSI治疗中,在卵巢刺激期间进行宫腔镜息肉切除术不会影响妊娠和活产率,并且可能消除冷冻的必要性。

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本文引用的文献

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Endometrial polyps: Pathogenesis, sequelae and treatment.子宫内膜息肉:发病机制、后遗症及治疗
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Fresh versus frozen embryo transfers in assisted reproduction.辅助生殖中新鲜胚胎移植与冷冻胚胎移植的比较。
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Endometrial Polyps and Subfertility.子宫内膜息肉与生育力低下
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