Tabriz Health Services Management Research Center, Health Education and Health Promotion Department, Tabriz University of Medical Sciences, Tabriz, Iran; Medical Education Research Center, Health Management and Safety Promotion Research Institute, Tabriz University of Medical Sciences, Tabriz 5166/15731, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Nutrition, Bjørknes University College, Oslo, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
Nutr Metab Cardiovasc Dis. 2022 Nov;32(11):2483-2492. doi: 10.1016/j.numecd.2022.08.004. Epub 2022 Aug 14.
The metabolic syndrome (MetS) and its consequences are one of the main public health challenges worldwide. We conducted a systematic review and dose-response meta-analysis of studies that examined the association between screen time and the MetS among children and adolescents.
A systematic search was conducted using electronic databases, including PubMed, Scopus, ProQuest, and Cochrane Library, for studies published from 1963 up to 2 May 2022. In this systematic review and meta-analysis, observational studies with cross-sectional, case-control, and cohort design evaluating the association between screen time and MetS were included. Random effects models and linear and nonlinear dose-response meta-analyses were used to pool study results.
Seven studies were included in the meta-analysis. The summary OR of MetS among children and adolescents for the highest vs. lowest time of screen time was 1.64 (95% CI: 1.32-2.03, with little evidence of heterogeneity, I = 9.3%, P- = 0.35, n = 7 studies) and 1.64 (95% CI: 1.27-2.12, I = 27.7%, n = 6) for cross-sectional studies. Results persisted across several additional subgroup analyses. There was a linear positive association between screen time and the risk of MetS (P dose-response <0.0001; P nonlinearity = 0.64) with an OR of 1.29 (95% CI: 1.12-1.46) per 2 h/day increment in screen time.
The current dose-response meta-analysis suggested that increased screen time is associated with an increased risk of MetS among children and adolescents. Public health strategies may target unhealthy screen-based related behaviors to halt the development of MetS among children and adolescents.
代谢综合征（MetS）及其后果是全球主要的公共卫生挑战之一。我们对研究屏幕时间与儿童和青少年代谢综合征之间关系的观察性研究进行了系统回顾和剂量-反应荟萃分析。
使用电子数据库（包括 PubMed、Scopus、ProQuest 和 Cochrane Library）对 1963 年至 2022 年 5 月 2 日发表的研究进行了系统检索。在这项系统回顾和荟萃分析中，纳入了评估屏幕时间与代谢综合征之间关系的具有横断面、病例对照和队列设计的观察性研究。使用随机效应模型和线性及非线性剂量-反应荟萃分析来汇总研究结果。
有 7 项研究纳入荟萃分析。对于屏幕时间最高与最低组，儿童和青少年代谢综合征的汇总比值比（OR）为 1.64（95%可信区间：1.32-2.03，异质性较小，I²=9.3%，P=0.35，n=7 项研究）和 1.64（95%可信区间：1.27-2.12，I²=27.7%，n=6 项研究），用于横断面研究。在几个额外的亚组分析中结果仍然存在。屏幕时间与代谢综合征风险之间存在线性正相关（P 剂量-反应<0.0001；P 非线性=0.64），屏幕时间每增加 2 小时/天，OR 为 1.29（95%可信区间：1.12-1.46）。
目前的剂量-反应荟萃分析表明，屏幕时间增加与儿童和青少年代谢综合征风险增加相关。公共卫生策略可能针对不健康的基于屏幕的相关行为，以阻止儿童和青少年代谢综合征的发展。
