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菌血症所致肝脓肿及其与结肠癌的关联:菌血症是否为结肠癌的警示信号?

Liver Abscess due to Bacteremia and Its Association with Colonic Carcinoma: Is Bacteremia with an Alert for Colonic Carcinoma?

作者信息

Ota Ikuo, Takahashi Hitoshi, Ono Megumi, Yamamoto Seiki, Kogita Akihiro, Tsuda Hiroshi, Funai Sadao, Shigeoka Hironori, Hiraide Atsushi

机构信息

Department of Emergency Medicine, Nagayama Hospital, Kumatori, Japan.

Department of Surgery, Nagayama Hospital, Kumatori, Japan.

出版信息

Case Rep Gastroenterol. 2022 Aug 19;16(2):488-495. doi: 10.1159/000526158. eCollection 2022 May-Aug.

Abstract

Liver abscess caused by some kinds of group such as group has been recognized to associate with colorectal cancer. group with liver abscess has not been received much attention in this point of view. Here, we report the case of a 63-year-old man who developed liver abscess with , which belongs to the group. We confirmed that this case was accompanied by cecal carcinoma by colonoscopy. The tumor was a pathological lead point of intussusception of cecum. On the 26th day, open right hemicolectomy was performed. In this case, bacterial endophthalmitis was a complication due to bacteremia. The patient underwent ophthalmic surgery on the 98th day. Research investigating 16S rRNA of the mucosal colon microbiome reported that the gene was upregulated in patients with colorectal carcinoma. It is recommended that liver abscess with bacteremia should alert the clinician about the risks of carcinoma of the colon and abscess formation in distant organs. We here list the case reports of liver abscess caused by other than group, which was associated with colonic carcinoma, and suggest the need for further research about group.

摘要

由某些菌群(如 菌群)引起的肝脓肿已被认为与结直肠癌有关。从这一角度来看,由 菌群引起的肝脓肿尚未受到太多关注。在此,我们报告一例63岁男性患者,其发生了由属于 菌群的 引起的肝脓肿。通过结肠镜检查,我们确认该病例伴有盲肠癌。该肿瘤是盲肠套叠的病理起始点。在第26天,进行了开放性右半结肠切除术。在该病例中,细菌性眼内炎是菌血症引起的并发症。患者在第98天接受了眼科手术。一项关于结肠黏膜微生物群16S rRNA的研究报告称, 基因在结直肠癌患者中上调。建议伴有 菌血症的肝脓肿应提醒临床医生注意结肠癌和远处器官脓肿形成的风险。我们在此列出了除 菌群外由 引起的与结肠癌相关的肝脓肿病例报告,并建议对 菌群进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e321/9459598/5c14310dd238/crg-0016-0488-g01.jpg

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