Lin Jiaqi, Huang Shanshan, Liu Manli, Lin Lixia, Gu Jianjun, Duan Fang
Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research for Ocular Diseases, Guangzhou 510060, China.
J Ophthalmol. 2022 Sep 14;2022:1265556. doi: 10.1155/2022/1265556. eCollection 2022.
The aim of this study is to report the clinical characteristics, visual outcomes, and antibiotic susceptibilities of patients with endophthalmitis.
The medical records of patients with culture-proven endophthalmitis treated from June 2013 to December 2019 were reviewed.
This study included 36 eyes of 36 patients. The clinical settings included ocular trauma (15/36), corneal ulcer (9/36), postoperative endophthalmitis (5/36), endogenous (3/36), and unknown (4/36). Sixteen patients underwent evisceration, 13 patients underwent pars plana vitrectomy (PPV), 2 patients were treated with only intravitreal antibiotics, and 5 patients did not undergo surgery. Only one patient achieved a visual acuity of 20/400, and the others had all counting fingers or below. The cultured was 100% sensitive to gentamicin, tobramycin, amikacin, ciprofloxacin, and levofloxacin and, approximately 95% sensitive to meropenem, imipenem, and aztreonam.
The visual outcomes of endophthalmitis were very poor, and the evisceration rate remained high. has good susceptibility to gentamicin, tobramycin, amikacin, ciprofloxacin, and levofloxacin.
本研究旨在报告眼内炎患者的临床特征、视力预后及抗生素敏感性。
回顾性分析2013年6月至2019年12月间经培养证实的眼内炎患者的病历资料。
本研究纳入36例患者的36只眼。临床情况包括眼外伤（15/36）、角膜溃疡（9/36）、术后眼内炎（5/36）、内源性（3/36）及不明原因（4/36）。16例患者行眼球摘除术，13例患者行玻璃体切割术（PPV），2例患者仅接受玻璃体内抗生素治疗，5例患者未接受手术。仅1例患者视力达到20/400，其余患者视力均为指数或更低。培养物对庆大霉素、妥布霉素、阿米卡星、环丙沙星和左氧氟沙星100%敏感，对美罗培南、亚胺培南和氨曲南约95%敏感。
眼内炎的视力预后很差，眼球摘除率仍然很高。其对庆大霉素、妥布霉素、阿米卡星、环丙沙星和左氧氟沙星敏感性良好。
