Li Xiao-Jun, Guo Tian-Ze, Xie Yan, Bao Yan-Ping, Si Jia-Yue, Li Zhe, Xiong Yi-Ting, Li Hui, Li Su-Xia, Lu Lin, Wang Xue-Qin
Department of Psychiatry, Peking University International Hospital, Beijing 102206, China.
Department of Bioengineering, University of California San Diego, San Diego, CA 92093, United States.
World J Psychiatry. 2022 Aug 19;12(8):1076-1087. doi: 10.5498/wjp.v12.i8.1076.
In the post-pandemic era, the emergence of sporadic cases of coronavirus disease 2019 (COVID-19) and the scale of the pandemic are unpredictable. Therefore, the impact of sporadic cases of COVID-19 and isolation measures on mental health and sleep in different groups of people need to be analyzed.
To clarify the severity of psychological problems and insomnia of staff and community residents around a hospital with sporadic cases of COVID-19, and their relationship with quarantine location and long-term changes.
A cross-sectional survey was conducted on community residents and medical staff. Many of these medical staff had been subjected to different places of quarantine. Community residents did not experience quarantine. Hospital anxiety and depression scale (HADS), acute stress disorder scale (ASDS) and insomnia severity index (ISI) were used to evaluate anxiety and depression, acute stress disorder symptoms, and the severity of insomnia. Additionally, we conducted a 1-year follow-up study on medical staff, with related scales measurement immediately after and one year after the 2-wk quarantine period.
We included 406 medical staff and 226 community residents. The total scores of ISI and subscale in HADS of community residents were significantly higher than that of medical staff. Further analysis of medical staff who experienced quarantine showed that 134 were quarantined in hotels, 70 in hospitals and 48 at home. Among all subjects, the proportions of HADS, ASDS and ISI scores above normal cutoff value were 51.94%, 19.17% and 31.11%, respectively. Multivariable logistic regression analysis found that subjects with higher total ASDS scores had a greater risk to develop anxiety and depression. The total ISI score for medical staff in hotel quarantine was significantly higher than those in home quarantine. Total 199 doctors and nurses who completed the 1-year follow-up study. Compared with baseline, HADS and ASDS scores decreased significantly one year after the end of quarantine, while ISI scores did not change significantly.
Sporadic COVID-19 cases had a greater psychological impact on residents in surrounding communities, mainly manifested as insomnia and depressive symptoms. Hotel quarantine aggravated the severity of insomnia in medical staff, whose symptoms lasted ≥ 1 year.
在疫情后时代，2019冠状病毒病（COVID-19）散发病例的出现以及疫情规模难以预测。因此，需要分析COVID-19散发病例及隔离措施对不同人群心理健康和睡眠的影响。
明确某有COVID-19散发病例医院周边工作人员及社区居民心理问题和失眠的严重程度，以及它们与隔离地点和长期变化的关系。
对社区居民和医务人员进行横断面调查。这些医务人员中有许多人曾在不同地点接受隔离。社区居民未经历隔离。采用医院焦虑抑郁量表（HADS）、急性应激障碍量表（ASDS）和失眠严重程度指数（ISI）评估焦虑抑郁、急性应激障碍症状以及失眠严重程度。此外，我们对医务人员进行了为期1年的随访研究，在2周隔离期结束后及1年后立即进行相关量表测量。
我们纳入了406名医务人员和226名社区居民。社区居民ISI总分及HADS分量表得分显著高于医务人员。对经历隔离的医务人员进一步分析显示，134人在酒店隔离，70人在医院隔离，48人在家隔离。在所有研究对象中，HADS、ASDS和ISI得分高于正常临界值的比例分别为51.94%、19.17%和31.11%。多变量逻辑回归分析发现，ASDS总分较高的研究对象发生焦虑抑郁的风险更大。酒店隔离的医务人员ISI总分显著高于居家隔离者。共有199名医生和护士完成了1年的随访研究。与基线相比，隔离结束1年后HADS和ASDS得分显著下降，而ISI得分无显著变化。
COVID-19散发病例对周边社区居民心理影响更大，主要表现为失眠和抑郁症状。酒店隔离加重了医务人员失眠的严重程度，其症状持续≥1年。
