Neville Catriona, Gwynn Tamsin, Young Karen, Jordan Elizabeth, Malhotra Raman, Nduka Charles, Kannan Ruben Yap
Facial Palsy Unit, Queen Victoria Hospital, East Grinstead, United Kingdom.
Department of Psychological Therapy, Queen Victoria Hospital, East Grinstead, United Kingdom.
Arch Plast Surg. 2022 Sep 23;49(5):633-641. doi: 10.1055/s-0042-1756352. eCollection 2022 Sep.
In chronic facial palsy, synkinetic muscle overactivity and shortening causes muscle stiffness resulting in reduced movement and functional activity. This article studies the role of multimodal therapy in improving outcomes. Seventy-five facial palsy patients completed facial rehabilitation before being successfully discharged by the facial therapy team. The cohort was divided into four subgroups depending on the time of initial attendance post-onset. The requirement for facial therapy, chemodenervation, or surgery was assessed with East Grinstead Grade of Stiffness (EGGS). Outcomes were measured using the Facial Grading Scale (FGS), Facial Disability Index, House-Brackmann scores, and the Facial Clinimetric Evaluation scale. FGS composite scores significantly improved posttherapy (mean-standard deviation, 60.13 ± 23.24 vs. 79.9 ± 13.01; confidence interval, -24.51 to -14.66, < 0.0001). Analysis of FGS subsets showed that synkinesis also reduced significantly ( < 0.0001). Increasingly, late clinical presentations were associated with patients requiring longer durations of chemodenervation treatment ( < 0.01), more chemodenervation episodes ( < 0.01), increased doses of botulinum toxin ( < 0.001), and having higher EGGS score ( < 0.001). This study shows that multimodal facial rehabilitation in the management of facial palsy is effective, even in patients with chronically neglected synkinesis. In terms of the latency periods between facial palsy onset and treatment initiation, patients presenting later than 2 years were still responsive to multimodal treatment albeit to a lesser extent, which we postulate is due to increasing muscle contracture within their facial muscles.
在慢性面瘫中,联动肌的过度活动和缩短会导致肌肉僵硬,从而致使运动和功能活动减少。本文研究多模式治疗在改善疗效方面的作用。
75例面瘫患者在接受面部治疗团队成功出院前完成了面部康复。根据发病后首次就诊时间,该队列被分为四个亚组。使用伊斯特格林德僵硬分级(EGGS)评估对面部治疗、化学去神经支配或手术的需求。使用面部分级量表(FGS)、面部残疾指数、House-Brackmann评分和面部临床计量评估量表来测量结果。
治疗后FGS综合评分显著改善(均值 - 标准差,60.13±23.24对79.9±13.01;置信区间,-24.51至-14.66,P<0.0001)。FGS亚组分析表明联动现象也显著减少(P<0.0001)。越来越多的晚期临床表现与需要更长时间化学去神经支配治疗的患者相关(P<0.01),化学去神经支配发作次数更多(P<0.01),肉毒杆菌毒素剂量增加(P<0.001),以及EGGS评分更高(P<0.001)。
本研究表明,多模式面部康复治疗面瘫是有效的,即使是对于长期被忽视的联动患者。就面瘫发作与治疗开始之间的潜伏期而言,发病超过2年就诊的患者对多模式治疗仍有反应,尽管程度较小,我们推测这是由于其面部肌肉内肌肉挛缩增加所致。