• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

面瘫患者多模式治疗的比较研究

Comparative Study of Multimodal Therapy in Facial Palsy Patients.

作者信息

Neville Catriona, Gwynn Tamsin, Young Karen, Jordan Elizabeth, Malhotra Raman, Nduka Charles, Kannan Ruben Yap

机构信息

Facial Palsy Unit, Queen Victoria Hospital, East Grinstead, United Kingdom.

Department of Psychological Therapy, Queen Victoria Hospital, East Grinstead, United Kingdom.

出版信息

Arch Plast Surg. 2022 Sep 23;49(5):633-641. doi: 10.1055/s-0042-1756352. eCollection 2022 Sep.

DOI:10.1055/s-0042-1756352
PMID:36159376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9507561/
Abstract

In chronic facial palsy, synkinetic muscle overactivity and shortening causes muscle stiffness resulting in reduced movement and functional activity. This article studies the role of multimodal therapy in improving outcomes.  Seventy-five facial palsy patients completed facial rehabilitation before being successfully discharged by the facial therapy team. The cohort was divided into four subgroups depending on the time of initial attendance post-onset. The requirement for facial therapy, chemodenervation, or surgery was assessed with East Grinstead Grade of Stiffness (EGGS). Outcomes were measured using the Facial Grading Scale (FGS), Facial Disability Index, House-Brackmann scores, and the Facial Clinimetric Evaluation scale.  FGS composite scores significantly improved posttherapy (mean-standard deviation, 60.13 ± 23.24 vs. 79.9 ± 13.01; confidence interval, -24.51 to -14.66,  < 0.0001). Analysis of FGS subsets showed that synkinesis also reduced significantly (  < 0.0001). Increasingly, late clinical presentations were associated with patients requiring longer durations of chemodenervation treatment (  < 0.01), more chemodenervation episodes (  < 0.01), increased doses of botulinum toxin (  < 0.001), and having higher EGGS score (  < 0.001).  This study shows that multimodal facial rehabilitation in the management of facial palsy is effective, even in patients with chronically neglected synkinesis. In terms of the latency periods between facial palsy onset and treatment initiation, patients presenting later than 2 years were still responsive to multimodal treatment albeit to a lesser extent, which we postulate is due to increasing muscle contracture within their facial muscles.

摘要

在慢性面瘫中,联动肌的过度活动和缩短会导致肌肉僵硬,从而致使运动和功能活动减少。本文研究多模式治疗在改善疗效方面的作用。

75例面瘫患者在接受面部治疗团队成功出院前完成了面部康复。根据发病后首次就诊时间,该队列被分为四个亚组。使用伊斯特格林德僵硬分级(EGGS)评估对面部治疗、化学去神经支配或手术的需求。使用面部分级量表(FGS)、面部残疾指数、House-Brackmann评分和面部临床计量评估量表来测量结果。

治疗后FGS综合评分显著改善(均值 - 标准差,60.13±23.24对79.9±13.01;置信区间,-24.51至-14.66,P<0.0001)。FGS亚组分析表明联动现象也显著减少(P<0.0001)。越来越多的晚期临床表现与需要更长时间化学去神经支配治疗的患者相关(P<0.01),化学去神经支配发作次数更多(P<0.01),肉毒杆菌毒素剂量增加(P<0.001),以及EGGS评分更高(P<0.001)。

本研究表明,多模式面部康复治疗面瘫是有效的,即使是对于长期被忽视的联动患者。就面瘫发作与治疗开始之间的潜伏期而言,发病超过2年就诊的患者对多模式治疗仍有反应,尽管程度较小,我们推测这是由于其面部肌肉内肌肉挛缩增加所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/f648502c5224/10-1055-s-0042-1756352-i21316-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/26ae9563c483/10-1055-s-0042-1756352-i21316-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/d4cc76a45499/10-1055-s-0042-1756352-i21316-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/caf1b2f1f22b/10-1055-s-0042-1756352-i21316-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/b620a18ea9e1/10-1055-s-0042-1756352-i21316-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/70ebdae74cbb/10-1055-s-0042-1756352-i21316-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/f648502c5224/10-1055-s-0042-1756352-i21316-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/26ae9563c483/10-1055-s-0042-1756352-i21316-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/d4cc76a45499/10-1055-s-0042-1756352-i21316-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/caf1b2f1f22b/10-1055-s-0042-1756352-i21316-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/b620a18ea9e1/10-1055-s-0042-1756352-i21316-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/70ebdae74cbb/10-1055-s-0042-1756352-i21316-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f904/9507561/f648502c5224/10-1055-s-0042-1756352-i21316-4.jpg

相似文献

1
Comparative Study of Multimodal Therapy in Facial Palsy Patients.面瘫患者多模式治疗的比较研究
Arch Plast Surg. 2022 Sep 23;49(5):633-641. doi: 10.1055/s-0042-1756352. eCollection 2022 Sep.
2
Masseteric-to-Facial Nerve Transfer and Selective Neurectomy for Rehabilitation of the Synkinetic Smile.咬肌-面神经转移和选择性神经切除术治疗协同性微笑康复。
JAMA Facial Plast Surg. 2019 Dec 1;21(6):504-510. doi: 10.1001/jamafacial.2019.0689.
3
Anatomic Considerations of Perinasal Musculature for Improved Dental Show During Smile in Facial Synkinesis.鼻旁肌肉解剖学考虑因素对面部联动性微笑中牙齿显露改善的影响。
Facial Plast Surg Aesthet Med. 2022 Mar-Apr;24(2):89-94. doi: 10.1089/fpsam.2020.0610. Epub 2021 Aug 26.
4
Chemodenervation Algorithm: Functional and Aesthetic Considerations for Facial Harmony in Patients with Post-Facial Paralysis Synkinesis.化学去神经支配算法:面瘫后联带运动患者面部和谐的功能和审美考虑。
Facial Plast Surg Aesthet Med. 2023 Nov-Dec;25(6):512-518. doi: 10.1089/fpsam.2022.0206. Epub 2023 May 16.
5
Targeted chemodenervation of the posterior belly of the digastric muscle for the management of jaw discomfort in facial synkinesis.靶向化学去神经支配二腹肌后腹以治疗面部联动中的下颌不适。
J Plast Reconstr Aesthet Surg. 2021 Dec;74(12):3437-3442. doi: 10.1016/j.bjps.2021.05.045. Epub 2021 Jun 9.
6
Therapeutic strategies in post-facial paralysis synkinesis in pediatric patients.小儿面瘫后面神经联带运动的治疗策略。
J Plast Reconstr Aesthet Surg. 2012 Aug;65(8):1009-18. doi: 10.1016/j.bjps.2012.03.026. Epub 2012 Apr 6.
7
Outcomes of Buccinator Treatment With Botulinum Toxin in Facial Synkinesis.颊肌肉毒毒素治疗面部联动的疗效。
JAMA Facial Plast Surg. 2018 May 1;20(3):196-201. doi: 10.1001/jamafacial.2017.1385.
8
The use of the facial clinimetric evaluation scale as a patient-based grading system in Bell's palsy.面瘫患者面部临床计量评估量表作为一种基于患者的分级系统的应用。
Laryngoscope. 2013 May;123(5):1256-60. doi: 10.1002/lary.23790. Epub 2013 Apr 2.
9
IncobotulinumtoxinA treatment of facial nerve palsy after neurosurgery.经外科手术后面神经麻痹的注射用冻干粉型 botulinum 神经毒素 A 治疗。
J Neurol Sci. 2017 Oct 15;381:130-134. doi: 10.1016/j.jns.2017.08.3244. Epub 2017 Aug 24.
10
Measuring the Potential Effects of Mirror Therapy Added to the Gold Standard Facial Neuromuscular Retraining in Patients With Chronic Peripheral Facial Palsy: Protocol for a Randomized Controlled Trial.评估在慢性周围性面瘫患者的金标准面部神经肌肉再训练基础上增加镜像疗法的潜在效果:一项随机对照试验方案
JMIR Res Protoc. 2023 Jul 7;12:e47709. doi: 10.2196/47709.

引用本文的文献

1
Ophthalmic and periocular management of facial nerve palsy.面神经麻痹的眼科及眼周治疗
Saudi J Ophthalmol. 2025 Feb 24;39(2):117-124. doi: 10.4103/sjopt.sjopt_3_25. eCollection 2025 Apr-Jun.
2
A Comparative Study of Platysmal Myoneurectomy With Variations of Selective Neurectomies in Post-Facial Palsy Synkinesis.在面瘫后联动中,颈阔肌肌神经切除术与选择性神经切除术不同术式的比较研究。
Microsurgery. 2025 Mar;45(3):e70040. doi: 10.1002/micr.70040.
3
Approaches to the Management of Synkinesis: A Scoping Review.关于联带运动管理的方法:范围综述。

本文引用的文献

1
Facial synkinesis: A distressing sequela of facial palsy.面肌联动:面瘫的一种令人苦恼的后遗症。
Ear Nose Throat J. 2024 Jun;103(6):NP382-NP391. doi: 10.1177/01455613211054627. Epub 2021 Nov 26.
2
Sunnybrook Facial Grading System: Intra-rater and Inter-rater Variabilities.阳光沙滩面部评分系统:组内和组间变异。
Otol Neurotol. 2021 Aug 1;42(7):1089-1094. doi: 10.1097/MAO.0000000000003140.
3
Modified Selective Neurectomy for the Treatment of Post-Facial Paralysis Synkinesis.改良选择性神经切断术治疗面瘫后联带运动
Facial Plast Surg. 2024 Aug;40(4):514-524. doi: 10.1055/a-2305-2007. Epub 2024 Apr 11.
4
[Telemedicine for patients with facial palsy : Current developments and options in otorhinolaryngologic treatment].[面神经麻痹患者的远程医疗:耳鼻咽喉科治疗的当前进展与选择]
HNO. 2024 Oct;72(10):702-710. doi: 10.1007/s00106-024-01449-4. Epub 2024 Mar 26.
Plast Reconstr Surg. 2019 May;143(5):1483-1496. doi: 10.1097/PRS.0000000000005590.
4
Facial Rehabilitation as Noninvasive Treatment for Chronic Facial Nerve Paralysis.面部康复作为慢性面神经麻痹的非侵入性治疗方法。
Otol Neurotol. 2019 Feb;40(2):241-245. doi: 10.1097/MAO.0000000000002107.
5
Facial Rehabilitation: Evaluation and Treatment Strategies for the Patient with Facial Palsy.面部康复:面瘫患者的评估与治疗策略
Otolaryngol Clin North Am. 2018 Dec;51(6):1151-1167. doi: 10.1016/j.otc.2018.07.011. Epub 2018 Sep 24.
6
Physical therapy for facial nerve palsy: applications for the physician.面神经麻痹的物理治疗:医师应用。
Curr Opin Ophthalmol. 2018 Sep;29(5):469-475. doi: 10.1097/ICU.0000000000000503.
7
Anxiety, depression, and hopelessness in patients before and after treatment for peripheral facial paralysis.周围性面瘫患者治疗前后的焦虑、抑郁和绝望情绪。
Ear Nose Throat J. 2018 Apr-May;97(4-5):E1-E4.
8
Botulinum toxin treatment for facial palsy: A systematic review.肉毒杆菌毒素治疗面神经麻痹:一项系统评价。
J Plast Reconstr Aesthet Surg. 2017 Jun;70(6):833-841. doi: 10.1016/j.bjps.2017.01.009. Epub 2017 Feb 16.
9
Platinum segments: a new platinum chain for adjustable upper eyelid loading.铂金段:一种用于可调节上睑负重的新型铂金链。
Br J Ophthalmol. 2015 Dec;99(12):1680-5. doi: 10.1136/bjophthalmol-2015-306869. Epub 2015 May 18.
10
The psychosocial impact of facial palsy: our experience in one hundred and twenty six patients.面瘫的社会心理影响:我们对126例患者的经验
Clin Otolaryngol. 2012 Dec;37(6):474-7. doi: 10.1111/coa.12026.