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西班牙加泰罗尼亚地区孕妇风疹血清流行病学研究

Seroepidemiology of rubella in pregnant females in Catalonia (Spain).

作者信息

Pumarola A, Salleras L, Vidal J, Canela J, Pumarola T, Jimenez de Anta M T, Coll J J, Peris M

出版信息

Rev Epidemiol Sante Publique. 1987;35(2):136-40.

PMID:3616052
Abstract

The seroepidemiological study carried out on a random sample of pregnant females aged between 15 and 45 in Catalonia (Spain) showed that the prevalence of antibodies found in the survey (97.5 +/- 2) varies from that shown by studies performed in continental areas of Europe and North America in the pre-vaccination era (80-90%) and is similar to that currently found in certain continental areas of Asia and Africa (about 95%) where the prevalence of the virus seems to be very high, and in certain industrialized countries which have implemented effective vaccination programmes (95-97%). Although 28.8% of the females surveyed stated that they had been vaccinated against rubella, it has not been possible to find any statistically significant differences as regards the prevalence of antibodies between vaccinated and nonvaccinated females. This suggests that the high prevalence of anti-rubella antibodies shown by the survey is due not so much to the existence of effective vaccination programmes as to the fact that the wild virus is extremely widespread among the Catalonian population, similar to certain continental areas of Asia and Africa.

摘要

对西班牙加泰罗尼亚地区15至45岁的怀孕女性随机样本进行的血清流行病学研究表明,调查中发现的抗体流行率(97.5 +/- 2)与欧洲大陆地区和北美在疫苗接种前时代进行的研究显示的流行率(80 - 90%)有所不同,与目前在亚洲和非洲某些大陆地区发现的流行率(约95%)相似,在这些地区病毒流行率似乎非常高,并且与实施了有效疫苗接种计划的某些工业化国家(95 - 97%)相似。尽管28.8%的受访女性表示她们接种过风疹疫苗,但在接种疫苗和未接种疫苗的女性之间,抗体流行率方面未发现任何统计学上的显著差异。这表明调查显示的抗风疹抗体高流行率与其说是由于有效的疫苗接种计划的存在,不如说是由于野生病毒在加泰罗尼亚人群中极其广泛传播,这与亚洲和非洲的某些大陆地区类似。

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Seroepidemiology of rubella in pregnant females in Catalonia (Spain).西班牙加泰罗尼亚地区孕妇风疹血清流行病学研究
Rev Epidemiol Sante Publique. 1987;35(2):136-40.
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[Susceptibility of pregnant women to rubella and the implications of immunization programs].[孕妇对风疹的易感性及免疫规划的影响]
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[Sero-epidemiological studies of the anti-rubella immunological status of a sample of the female population].[女性人群样本抗风疹免疫状态的血清流行病学研究]
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