Departamento de Nefrología, Hospital Universitario La Paz, Madrid, Spain.
Departamento de Nefrología, Hospital Universitario La Paz, Madrid, Spain; Instituto de investigación La Paz (IdiPAZ), Madrid, Spain.
Nefrologia (Engl Ed). 2021 May-Jun;41(3):329-336. doi: 10.1016/j.nefroe.2020.09.009. Epub 2021 Aug 19.
The 2019 coronavirus (COVID-19) is a viral infection caused by a new coronavirus that is affecting the entire world. There have been studies of patients on in-center hemodialysis (HD), but home dialysis population data are scarce. Our objective is to study the incidence and course of COVID-19 in a home dialysis unit (HDU) at the height of the pandemic.
an observational, retrospective study enrolling all patients diagnosed with COVID-19 from the HDU of Hospital Universitario La Paz [La Paz University Hospital] (Madrid, Spain) between March 10 and May 15, 2020. We collected clinical data from the HDU (57 patients on peritoneal dialysis [PD] and 22 patients on home hemodialysis [HHD]) and compared the clinical characteristics and course of patients with and without COVID-19 infection.
twelve patients were diagnosed with COVID-19 (9 PD; 3 HHD). There were no statistically significant differences in terms of clinical characteristics between patients with COVID-19 and the rest of the unit. The mean age was 62 ± 18.5 years; most were men (75%). All patients but one required hospitalization. Ten patients (83%) were discharged following a mean of 16.4 ± 9.7 days of hospitalization. Two patients were diagnosed while hospitalised for other conditions, and these were the only patients who died. Those who died were older than those who survived.
The incidence of COVID-19 in our HDU in Madrid at the height of the pandemic was high, especially in patients on PD. No potential benefit for preventing the infection in patients on home dialysis was observed. Advanced age and nosocomial transmission were the main factors linked to a worse prognosis.
2019 年冠状病毒(COVID-19)是一种由新型冠状病毒引起的病毒感染,正在影响全球。已经有研究报道了中心血液透析(HD)患者的情况,但家庭透析人群的数据很少。我们的目的是在大流行期间研究家庭透析单位(HDU)中 COVID-19 的发病率和病程。
一项观察性、回顾性研究,纳入了 2020 年 3 月 10 日至 5 月 15 日期间,在马德里拉帕兹大学医院(Hospital Universitario La Paz)HDU 中诊断出 COVID-19 的所有患者。我们从 HDU 收集了临床数据(57 名腹膜透析[PD]患者和 22 名家庭血液透析[HHD]患者),并比较了 COVID-19 感染患者和非感染患者的临床特征和病程。
12 名患者被诊断出患有 COVID-19(9 名 PD;3 名 HHD)。COVID-19 患者与单位其他患者的临床特征无统计学差异。平均年龄为 62±18.5 岁;大多数是男性(75%)。除 1 名患者外,所有患者均需住院治疗。10 名患者(83%)在平均住院 16.4±9.7 天后出院。2 名患者在因其他疾病住院时被诊断出患有 COVID-19,他们是唯一死亡的患者。死亡患者的年龄大于存活患者。
在大流行高峰期,马德里的 HDU 中 COVID-19 的发病率很高,尤其是 PD 患者。在家中进行血液透析的患者中,未观察到预防感染的潜在益处。高龄和医院内传播是与预后不良相关的主要因素。