National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.
CAS Key Laboratory of Nano-Bio Interface, CAS Center for Excellence in Nanoscience, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.
Langmuir. 2022 Oct 11;38(40):12148-12156. doi: 10.1021/acs.langmuir.2c01669. Epub 2022 Sep 27.
Traditional deltamethrin (DM) formulations (e.g., emulsifiable concentrates, wettable powders, etc.) have significant disadvantages of poor water dispersion stability, burst release, weak leaf affinity, short duration, poor efficacy, and high environmental toxicity. A nanomaterial-based pesticide delivery system (PDS) has provided effective strategies for green preparation and synergism of pesticide formulations. In this article, we developed carboxymethyl chitosan (CMCS)-modified graphene oxide (GO) as a vector for DM and constructed a pH-responsive PDS for control. GO-CMCS possesses excellent pesticide loading performance for DM (loading rate 87.76%). After being loading on GO-CMCS, the GO-CMCS-DM has a significantly improved dispersion stability in water. The GO-CMCS-DM exhibits pH-responsive controlled release performance, which can sustain the release of DM into the medium, maintaining an effective long-term concentration. Additionally, the leaf adhesion of GO-CMCS-DM is better than that for free DM, which can improve the pesticide utilization. Therefore, GO-CMCS-DM has a prolonged persistent period and sustained activity against . Considering the industrialization potential of GO, we believe that GO will play an important role in the pest control and antiepidemic fields.
传统的除虫菊酯（DM）制剂（例如乳油、可湿性粉剂等）存在着水分散稳定性差、爆发释放、叶亲和力弱、持效期短、效果差和环境毒性高等显著缺点。基于纳米材料的农药输送系统（PDS）为农药制剂的绿色制备和协同增效提供了有效的策略。在本文中，我们开发了羧甲基壳聚糖（CMCS）修饰的氧化石墨烯（GO）作为 DM 的载体，并构建了一种 pH 响应型 PDS 进行控制。GO-CMCS 对 DM 具有优异的农药负载性能（负载率为 87.76%）。在负载到 GO-CMCS 上后，GO-CMCS-DM 在水中的分散稳定性得到了显著提高。GO-CMCS-DM 表现出 pH 响应控制释放性能，能够将 DM 持续释放到介质中，保持有效的长期浓度。此外，GO-CMCS-DM 的叶片附着力优于游离 DM，可提高农药利用率。因此，GO-CMCS-DM 具有延长的持久性和对 的持续活性。考虑到 GO 的工业化潜力，我们相信 GO 将在病虫害防治和防疫领域发挥重要作用。
