State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, China.
National and Local Joint Engineering Research Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing, China.
Pest Manag Sci. 2022 Dec;78(12):5358-5365. doi: 10.1002/ps.7158. Epub 2022 Sep 15.
Traditional abamectin (Abm) formulations have several shortcomings, such as low water solubility, burst release behavior, poor photostability, and short persistence periods, which decrease their pesticidal activity and the risks they pose to the environment. Nanomaterial-based pesticide delivery systems (PDSs) provide new strategies for the efficient and safe application of pesticides. Here, we developed Abm-loaded graphene oxide (Abm/GO) as a PDS for the sustained release of Abm, which shows enhanced control efficacy against Plutella xylostella.
The hydrophobic Abm molecule was effectively loaded on GO nanocarrier by a physisorption method, which formed a uniform and stable Abm/GO nanoformulation. GO possesses high adsorption capacity and can effectively load Abm. The Abm/GO nanoformulation shows enhanced water dispersion stability and can remain stable during a 2-year storage period in contrast to the water-insoluble Abm. In addition, the Abm/GO nanoformulation exhibits sustained pesticide release behavior and possesses significantly improved anti-ultraviolet properties. Thus, the Abm/GO nanoformulation shows superior pesticidal activity compared with Abm. Abm/GO showed negligible toxicity to maize seedlings, and its GO nanocarrier can reduce the cytotoxicity of Abm to A549 cells.
GO-based PDSs can effectively overcome the disadvantages of traditional pesticides, such as their insolubility, burst release behavior, instability, and short persistence period. GO shows much future promise in agriculture in light of its industrialization potential. © 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
传统阿维菌素（Abm）制剂存在水溶性低、突释行为、光稳定性差和持效期短等缺点，降低了其杀虫活性和对环境的风险。基于纳米材料的农药输送系统（PDS）为农药的高效和安全应用提供了新的策略。在这里，我们开发了负载阿维菌素的氧化石墨烯（Abm/GO）作为阿维菌素的缓释 PDS，对小菜蛾表现出增强的控制效果。
疏水性 Abm 分子通过物理吸附法有效地负载在 GO 纳米载体上，形成均匀稳定的 Abm/GO 纳米制剂。GO 具有高吸附能力，可以有效负载 Abm。Abm/GO 纳米制剂具有增强的水分散稳定性，并且在 2 年的储存期内保持稳定，与不溶于水的 Abm 形成对比。此外，Abm/GO 纳米制剂表现出持续的农药释放行为，并且具有显著提高的抗紫外线性能。因此，Abm/GO 纳米制剂与 Abm 相比表现出优异的杀虫活性。Abm/GO 对玉米幼苗几乎没有毒性，其 GO 纳米载体可以降低 Abm 对 A549 细胞的细胞毒性。
基于 GO 的 PDS 可以有效克服传统农药的缺点，如不溶性、突释行为、不稳定性和短持效期。鉴于其工业化潜力，GO 在农业领域具有广阔的前景。© 2022 作者。Pest Management Science 由 John Wiley & Sons Ltd 代表化学工业协会出版。
