Al-Salihi Mohammed Maan, Hussein Muath, Al-Jebur Maryam Sabah, Rahman Sabrina, Ayyad Ali, Rahman Md Moshiur
Department of Neurosurgery, Hamad General Hospital, Doha, Qatar.
Department of Neurosurgery, Hamad General Hospital, Doha, Qatar.
Int J Surg Case Rep. 2022 Oct;99:107698. doi: 10.1016/j.ijscr.2022.107698. Epub 2022 Sep 24.
Paragangliomas of the spine are extremely rare, and they should be considered in the differential diagnosis of spinal tumors due to its overlapping clinical and radiological features with many spinal tumors.
In this article, we present a 30-year-old lady who presented with low back pain and radicular neuropathic pain at L1 dermatome which was intractable to medical surgery. Her magnetic resonance imaging (MRI) of the lumbosacral spine revealed a T1 isointense, T2 heterogeneously hyperintense intradural extramedullary lesion at the conus medullaris with strong homogenous enhancement on contrast administration. The lesion was surgically excised completely with L1 laminectomy, and the histopathological picture was suggestive of paraganglioma. The patient's complaints resolved fully postoperatively, and there was no evidence of recurrence on long-term follow-up.
Due to the absence of pathognomonic clinical or radiological features of paragangliomas, they should be taken into consideration in the differential diagnosis of spinal tumors. They share similar clinical and radiological features of schwannomas, ependymomas, and hemangioblastomas. The diagnosis is usually made postoperatively based on histopathological examination.
脊柱副神经节瘤极为罕见,因其临床和影像学特征与许多脊柱肿瘤重叠,故在脊柱肿瘤的鉴别诊断中应予以考虑。
在本文中,我们介绍了一位30岁女性,她表现为下背部疼痛和L1皮节的神经根性神经病理性疼痛,药物和手术治疗均难以缓解。她的腰骶部磁共振成像(MRI)显示圆锥处有一个T1等信号、T2不均匀高信号的硬膜内髓外病变,增强扫描呈均匀强化。通过L1椎板切除术将病变完全切除,组织病理学表现提示为副神经节瘤。患者术后症状完全缓解,长期随访无复发迹象。
由于副神经节瘤缺乏特征性的临床或影像学表现,在脊柱肿瘤的鉴别诊断中应考虑到它们。它们与神经鞘瘤、室管膜瘤和血管母细胞瘤具有相似的临床和影像学特征。诊断通常在术后根据组织病理学检查做出。