Bhardwaj Priyanka, Kaur Naviljyot, Selvaraj Manickam, Ghramh Hamed A, Al-Shehri Badria M, Singh Gursharan, Arya Shailendra Kumar, Bhatt Kalpana, Ghotekar Suresh, Mani Ravi, Chang Soon Woong, Ravindran Balasubramani, Awasthi Mukesh Kumar
College of Natural Resources and Environment, Northwest A&F University, Taicheng Road3# Shaanxi, Yangling 712100, China; Department of Biotechnology, University Institute of Engineering and Technology, Panjab University, Chandigarh, India.
Department of Biotechnology, University Institute of Engineering and Technology, Panjab University, Chandigarh, India.
Bioresour Technol. 2022 Nov;364:128031. doi: 10.1016/j.biortech.2022.128031. Epub 2022 Sep 24.
The main objective of this review is to provide up to date, brief, irrefutable, organized data on the conducted experiments on a range of emerging recalcitrant compounds such as Diclofenac (DCF), Chlorophenols (CPs), tetracycline (TCs), Triclosan (TCS), Bisphenol A (BPA) and Carbamazepine (CBZ). These compounds were selected from the categories of pharmaceutical contaminants (PCs), endocrine disruptors (EDs) and personal care products (PCPs) on the basis of their toxicity and concentration retained in the environment. In this context, detailed mechanism of laccase mediated degradation has been conversed that laccase assisted degradation occurs by one electron oxidation involving redox potential as underlying element of the process. Further, converging towards biotechnology, laccase immobilization increased removal efficiency, storage and reusability through various experimentally conducted studies. Laccase is being considered noteworthy as mediators facilitate laccase in oxidation of non-phenolic compounds and thereby increasing its substrate range which is being discussed in further in the review. The laccase assisted degradation mechanism of each compound has been elucidated but further studies to undercover proper degradation mechanisms needs to be performed.
本综述的主要目的是提供关于一系列新兴难降解化合物（如双氯芬酸（DCF）、氯酚（CPs）、四环素（TCs）、三氯生（TCS）、双酚A（BPA）和卡马西平（CBZ））所进行实验的最新、简要、无可辩驳且有条理的数据。这些化合物是根据其毒性和在环境中的残留浓度从药物污染物（PCs）、内分泌干扰物（EDs）和个人护理产品（PCPs）类别中挑选出来的。在此背景下，已探讨了漆酶介导降解的详细机制，即漆酶辅助降解通过单电子氧化发生，该过程以氧化还原电位作为基础要素。此外，在生物技术方面，通过各种实验研究表明，漆酶固定化提高了去除效率、储存性和可重复使用性。漆酶被认为值得关注，因为介质有助于漆酶氧化非酚类化合物，从而扩大其底物范围，本综述将对此进行进一步讨论。已阐明了每种化合物的漆酶辅助降解机制，但仍需开展进一步研究以揭示合适的降解机制。
