Institute of Experimental Psychology, University of Regensburg, Universitätsstraße 31, 93053, Regensburg, Germany.
Department of Psychology, National Taiwan University, Taipei, Taiwan.
Sci Rep. 2022 Sep 27;12(1):16143. doi: 10.1038/s41598-022-20592-y.
We investigated lateral modulation effects with functional magnetic resonance imaging. We presented radial sinusoidal gratings in random sequence: a scotoma grating with two arc-shaped blank regions (scotomata) in the periphery, one in the left and one in the right visual field, a center grating containing pattern only in the scotoma regions, and a full-field grating where the pattern occupied the whole screen. On each trial, one of the three gratings flickered in counterphase for 10 s, followed by a blank period. Observers were instructed to perform a fixation task and report whether filling-in was experienced during the scotoma condition. The results showed that the blood-oxygen-level-dependent signal was reduced in areas corresponding to the scotoma regions in the full-field compared to the center condition in V1 to V3 areas, indicating a lateral inhibition effect when the surround was added to the center pattern. The univariate analysis results showed no difference between the filling-in and no-filling-in trials. However, multivariate pattern analysis results showed that classifiers trained on activation pattern in V1 to V3 could differentiate between filling-in and no-filling-in trials, suggesting that the neural activation pattern in visual cortex correlated with the subjective percept.
我们使用功能磁共振成像研究了横向调制效应。我们以随机顺序呈现了径向正弦光栅：一个带有两个弧形空白区域（盲点）的外围光栅，一个在左视野，一个在右视野，一个中心光栅，其图案仅在盲点区域，一个全屏幕光栅，其图案占据整个屏幕。在每次试验中，三个光栅中的一个以反相闪烁 10 秒，然后是空白期。要求观察者执行一个固定任务，并报告在盲点条件下是否经历了填充。结果表明，与中心条件相比，V1 到 V3 区域的全视野中对应于盲点区域的血氧水平依赖信号减少，表明当周围区域添加到中心图案时会产生横向抑制效应。单变量分析结果表明，填充和不填充试验之间没有差异。然而，多元模式分析结果表明，在 V1 到 V3 的激活模式上训练的分类器可以区分填充和不填充的试验，这表明视觉皮层的神经激活模式与主观感知相关。
