Department of Neurology, Konyang University College of Medicine, Daejeon, Korea.
Yonsei Med J. 2022 Oct;63(10):966-970. doi: 10.3349/ymj.2022.0038.
The global coronavirus disease 2019 (COVID-19) pandemic spurred an urgent need for vaccination and herd immunity. Recently, mRNA vaccines for COVID-19 have been used widely despite reports of several adverse events. Most adverse effects are mild, although a few are associated with neurological complications. Unfortunately, there is a scarcity of information on peripheral nerve complications after COVID-19 mRNA vaccination. We report the case of an immunocompetent young male patient who suffered from ipsilateral wrist drop with multiple lymphadenopathy in the cervical and axillary region after Pfizer-BioNTech vaccination. He experienced unilateral wrist drop, which significantly improved with corticosteroid treatment. Based on knowledge of this adverse effect, careful surveillance and increased awareness are needed for early diagnosis. To the best of our knowledge, this is the first reported case in the English literature of radial neuropathy resulting in wrist drop in a recently vaccinated and young immunocompetent patient.
全球 2019 年冠状病毒病（COVID-19）大流行促使人们迫切需要接种疫苗和群体免疫。尽管有报道称出现了几种不良事件，但最近仍广泛使用了用于 COVID-19 的 mRNA 疫苗。大多数不良反应是轻微的，但也有一些与神经系统并发症有关。不幸的是，关于 COVID-19 mRNA 疫苗接种后周围神经并发症的信息很少。我们报告了一例免疫功能正常的年轻男性患者，他在接种辉瑞-生物科技疫苗后出现同侧腕下垂和颈、腋窝多处淋巴结病。他经历了单侧腕下垂，经皮质类固醇治疗后显著改善。根据对这种不良反应的认识，需要进行仔细的监测和提高认识，以便及早诊断。据我们所知，这是首例在英语文献中报道的最近接种疫苗且免疫功能正常的年轻患者发生桡神经病变导致腕下垂的病例。
