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过氧化氢碱性溶液中超氧自由基的产生以及超氧化物歧化酶对该体系的影响。

Generation of superoxide radicals in alkaline solutions of hydrogen peroxide and the effect of superoxide dismutase on this system.

作者信息

Symonyan M A, Nalbandyan R M

出版信息

Biochim Biophys Acta. 1979 Mar 22;583(3):279-86. doi: 10.1016/0304-4165(79)90452-5.

DOI:10.1016/0304-4165(79)90452-5
PMID:36170
Abstract

Superoxide radicals in high concentrations were generated from alkaline H2O2 without using catalysts or irradiation. The dependence of the intensity and parameters of the superoxide radical EPR spectrum on pH, temperature, viscosity and H2O2 concentration were studied. The observed changes are explained on the base of matrix effects. The addition of superoxide dismutase to alkaline H2O2 led initially to a drop in the EPR spectrum intensity, followed by an increase in the concentration of superoxide radicals.

摘要

在不使用催化剂或辐射的情况下,通过碱性过氧化氢生成了高浓度的超氧自由基。研究了超氧自由基电子顺磁共振(EPR)谱的强度和参数对pH值、温度、粘度和过氧化氢浓度的依赖性。基于基质效应解释了观察到的变化。向碱性过氧化氢中添加超氧化物歧化酶最初导致EPR谱强度下降,随后超氧自由基浓度增加。

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