[头孢菌素：微生物学和药代动力学特性及其在儿科的应用]
[Cephalosporins: microbiological and pharmacokinetic properties, application to pediatrics].
作者信息
Geelen S P, Roord J J, Neeleman C, Fleer A
出版信息
Tijdschr Kindergeneeskd. 1987 Jul;55(3):81-6.
Many cephalosporins are presently available for clinical use. Although the cephalosporins are excellent antimicrobial agents for many infectious diseases in childhood, they have not replaced the older antibiotic regiments. In fact they offer the pediatrician a broader range of choices in treatment. This article gives a review on microbiological and pharmacokinetic properties of cephalosporins and an indication for the use of cephalosporins in pediatric therapy.
目前有许多头孢菌素可供临床使用。尽管头孢菌素是治疗儿童多种传染病的优秀抗菌药物，但它们并未取代 older antibiotic regiments（此处“older antibiotic regiments”可能有误，推测可能是“older antibiotic regimens”，即“传统抗生素疗法”）。事实上，它们为儿科医生提供了更广泛的治疗选择。本文综述了头孢菌素的微生物学和药代动力学特性以及其在儿科治疗中的应用指征。
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