氯霉素对大肠杆菌K-12中亚硝基胍诱变作用的增强效应。
Enchancement of nitrosoguanidine mutagenesis by chloramphenicol in Escherichia coli K-12.
作者信息
Sklar R
出版信息
J Bacteriol. 1978 Oct;136(1):460-2. doi: 10.1128/jb.136.1.460-462.1978.
Abstract
N-methyl-N'-nitro-N-nitrosoguanidine-induced mutagenesis in E. coli K-12 can be enchanced up to 50-fold by the addition of chloramphenicol with minimal effect on survival. Chloramphenicol does not produce the expected proportionate increase in closely linked double mutations.
摘要
在大肠杆菌K-12中，通过添加氯霉素，N-甲基-N'-硝基-N-亚硝基胍诱导的诱变作用可增强至50倍，而对存活率的影响最小。氯霉素不会使紧密连锁的双突变按预期比例增加。
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本文引用的文献
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