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本文引用的文献

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Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin.在大环内酯类抗生素泰乐菌素生物合成中受阻的弗氏链霉菌突变体的特性。
Antimicrob Agents Chemother. 1981 Aug;20(2):214-25. doi: 10.1128/AAC.20.2.214.
2
Role of the uvrE gene product and of inducible O6-methylguanine removal in the induction of mutations by N-methyl-N'-nitro-N-nitrosoguanidine in Escherichia coli.uvrE基因产物及诱导性O6-甲基鸟嘌呤去除在大肠杆菌中N-甲基-N'-硝基-N-亚硝基胍诱导突变中的作用。
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Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin.大环内酯类抗生素泰乐菌素的生物合成。从泰乐内酯到泰乐菌素的优选途径。
J Antibiot (Tokyo). 1983 Feb;36(2):131-41. doi: 10.7164/antibiotics.36.131.
4
Involvement of the activated form of RecA protein in SOS mutagenesis and stable DNA replication in Escherichia coli.RecA蛋白的活化形式参与大肠杆菌中的SOS诱变和稳定DNA复制。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7539-43. doi: 10.1073/pnas.81.23.7539.
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Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.大肠杆菌中的诱变作用及对脱氧核糖核酸损伤的诱导反应
Microbiol Rev. 1984 Mar;48(1):60-93. doi: 10.1128/mr.48.1.60-93.1984.
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Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli.大肠杆菌中O-烷基化DNA嘧啶的诱导修复
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DNA repair enzymes.DNA修复酶
Annu Rev Biochem. 1982;51:61-87. doi: 10.1146/annurev.bi.51.070182.000425.
8
Mutangenesis by N-methyl-N'-nitro-N-nitrosoguanidine (NTG) in Streptomyces coelicolor.天蓝色链霉菌中N-甲基-N'-硝基-N-亚硝基胍（NTG）诱导的诱变作用
Mutat Res. 1970 Feb;9(2):167-82. doi: 10.1016/0027-5107(70)90055-2.
9
The replication of the Escherichia coli chromosome studied by sequential nitrosoguanidine mutagenesis.通过连续亚硝基胍诱变研究大肠杆菌染色体的复制。
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Directed mutation in Streptomyces lipmanii.里氏链霉菌中的定向突变
Can J Microbiol. 1974 Nov;20(11):1479-85. doi: 10.1139/m74-231.

弗氏链霉菌中氯霉素对N-甲基-N'-硝基-N-亚硝基胍诱变的适应性反应及增强作用

Adaptive response and enhancement of N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis by chloramphenicol in Streptomyces fradiae.

作者信息

Baltz R H, Stonesifer J

出版信息

J Bacteriol. 1985 Nov;164(2):944-6. doi: 10.1128/jb.164.2.944-946.1985.

DOI:10.1128/jb.164.2.944-946.1985
PMID:4055703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC214347/
Abstract

Streptomyces fradiae expressed an adaptive response to treatment with small doses of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) that caused a reduction in mutagenesis by treatment with larger doses of MNNG. Treatment of S. fradiae with high levels of MNNG in the presence of chloramphenicol caused enhancement of mutagenesis, independent of the adaptive response.

摘要

弗氏链霉菌对小剂量N-甲基-N'-硝基-N-亚硝基胍（MNNG）处理表现出适应性反应，这种反应导致用大剂量MNNG处理时诱变作用降低。在氯霉素存在的情况下，用高水平MNNG处理弗氏链霉菌会导致诱变作用增强，且与适应性反应无关。