Department of Electrical Engineering, Columbia University, 500 W 120th St., New York, NY, 10027, USA.
Department of Emergency Medicine, Morgan Stanley Children's Hospital of New York Presbyterian at Columbia University Medical Center, New York, 10032, USA.
Sci Rep. 2022 Sep 28;12(1):16184. doi: 10.1038/s41598-022-20721-7.
Ultrasound imaging provides the means for non-invasive real-time diagnostics of the internal structure of soft tissue in living organisms. However, the majority of commercially available ultrasonic transducers have rigid interfaces which cannot conform to highly-curved surfaces. These geometric limitations can introduce a signal-quenching air gap for certain topographies, rendering accurate imaging difficult or impractical. Here, we demonstrate a 256-element flexible two-dimensional (2D) ultrasound piezoelectric transducer array with geometric phase correction. We show surface-conformable real-time B-mode imaging, down to an extreme radius of curvature of 1.5 cm, while maintaining desirable performance metrics such as high signal-to-noise ratio (SNR) and minimal elemental cross-talk at all stages of bending. We benchmark the array capabilities by resolving reflectors buried at known locations in a medical-grade tissue phantom, and demonstrate how phase correction can improve image reconstruction on curved surfaces. With the current array design, we achieve an axial resolution of ≈ 2 mm at clinically-relevant depths in tissue, while operating the array at 1.4 MHz with a bandwidth of ≈ 41%. We use our prototype to image the surface of the human humerus at different positions along the arm, demonstrating proof-of-concept applicability for real-time diagnostics using phase-corrected flexible ultrasound probes.
超声成像是一种非侵入式实时诊断活体软组织内部结构的手段。然而,大多数市售的超声换能器具有刚性界面,无法适应高度弯曲的表面。这些几何限制会在某些形貌下引入信号衰减的气隙,使得精确成像变得困难或不切实际。在这里,我们展示了一种具有几何相位校正的 256 元柔性二维(2D)超声压电换能器阵列。我们展示了表面顺应的实时 B 模式成像,其最小曲率半径可达 1.5cm,同时在弯曲的各个阶段保持了高信噪比(SNR)和最小的单元串扰等理想性能指标。我们通过在医用组织体模中已知位置的反射器来验证该阵列的性能,并展示了相位校正如何改善曲面的图像重建。使用当前的阵列设计,我们在组织中临床相关的深度实现了约 2mm 的轴向分辨率,同时以 1.4MHz 的频率工作,带宽约为 41%。我们使用我们的原型在手臂的不同位置对人体肱骨表面进行成像,证明了使用相位校正的柔性超声探头进行实时诊断的概念验证适用性。