Sharma Nitin, Xue Xiangming, Iyer Ashwin, Jiang Xiaoning, Roque Daniel
Joint Department of Biomedical Engineering, North Carolina State University, Raleigh, NC and University of North Carolina-Chapel Hill, NC.
Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC.
Curr Opin Biomed Eng. 2023 Dec;28. doi: 10.1016/j.cobme.2023.100484. Epub 2023 Jun 24.
Despite several decades of research investigating the use of peripheral electrical stimulation (ES) for tremor suppression in an upper limb, ES design for effective tremor suppression remains elusive. The article reviews sensing approaches to measure limb tremors and existing musculoskeletal models of tremor and their use in closed-loop suppression control. We also motivate a case for incorporating ultrasound (US) imaging into the closed-loop control for increased tremor suppression efficacy. When combined with wearable US transducers, the novel approach could be a promising technique to advance musculoskeletal models that investigate tremor mechanisms and new ES closed-loop techniques with personalized stimulation parameters for tremor suppression.
尽管数十年来一直在研究使用外周电刺激（ES）来抑制上肢震颤，但用于有效抑制震颤的ES设计仍然难以捉摸。本文回顾了测量肢体震颤的传感方法、现有的震颤肌肉骨骼模型及其在闭环抑制控制中的应用。我们还提出了将超声（US）成像纳入闭环控制以提高震颤抑制效果的理由。当与可穿戴式超声换能器结合使用时，这种新方法可能是一种很有前景的技术，可推动用于研究震颤机制的肌肉骨骼模型以及具有个性化刺激参数的新型ES闭环震颤抑制技术的发展。
