Shobokshi O A, Serebour F E
Trans R Soc Trop Med Hyg. 1987;81(2):219-21. doi: 10.1016/0035-9203(87)90220-3.
Of the 1050 sera of acute viral hepatitis patients admitted to the Infectious Diseases Hospital in Jeddah, Saudi Arabia, over a one-year period, 40.9% were due to hepatitis A, 21.5% to hepatitis B, and 37.6% to non-A, non-B (NANB) hepatitis. The mean age for hepatitis A patients was 4 +/- 2.4 years, with no sex preponderance. The mean ages for hepatitis B and NANB were 26.1 +/- 11.9 and 28.8 +/- 14.2 years, respectively. A male to female ratio of 2:1 was noticed for both. 10% of HBsAg patients were positive for anti-delta. 32% of NANB cases were excluded on the bases of possessing specific IgM against cytomegalovirus (CMV), herpes simplex virus (HSV), Epstein-Barr virus (EBV) or Treponema pallidum. Only 9% of NANB cases had a history of blood transfusion. In conclusion, nearly all cases of acute jaundice in Saudi children are due to hepatitis A, whereas hepatitis B and NANB generally occur in adults. Other viruses such as CMV, HSV, and EBV are highly prevalent and must be excluded in all cases of NANB hepatitis.
在沙特阿拉伯吉达传染病医院收治的1050例急性病毒性肝炎患者的血清样本中，为期一年的研究显示，40.9%的病例由甲型肝炎引起，21.5%由乙型肝炎引起，37.6%由非甲非乙型（NANB）肝炎引起。甲型肝炎患者的平均年龄为4±2.4岁，无性别差异。乙型肝炎和NANB肝炎患者的平均年龄分别为26.1±11.9岁和28.8±14.2岁。两者的男女比例均为2:1。10%的HBsAg患者抗delta呈阳性。32%的NANB病例因检测到针对巨细胞病毒（CMV）、单纯疱疹病毒（HSV）、爱泼斯坦-巴尔病毒（EBV）或梅毒螺旋体的特异性IgM而被排除。只有9%的NANB病例有输血史。总之，沙特儿童的急性黄疸病例几乎都由甲型肝炎引起，而乙型肝炎和NANB肝炎通常发生在成年人中。其他病毒如CMV、HSV和EBV非常普遍，在所有NANB肝炎病例中都必须排除。
