Suppr超能文献

在极低出生体重儿队列中,30 岁以后的社会经济结局。

Socioeconomic outcomes beyond 30 years of age in a cohort born with very low birth weight.

机构信息

Department of Neonatology, Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.

Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Hilleroed, Denmark.

出版信息

Acta Paediatr. 2023 Jan;112(1):78-84. doi: 10.1111/apa.16557. Epub 2022 Oct 10.

Abstract

AIM

As survival of infants born prematurely has increased dramatically, questions on long-term consequences have emerged. Our aim was to investigate long-term effects of very low birth weight on socioeconomic outcomes.

METHODS

One hundred and fifty very low birth weight infants (VLBW) born from 1980 to 1982 at Rigshospitalet, Denmark, who had previously been followed up at age 2, 4 and 18 years, were compared to cohorts of low birth weight, normal birth weight (NBW) and a national population-based reference cohort. From the Danish national registers we obtained data regarding educational level, financial independence and living arrangements. In addition, we used the previously published results from the three cohorts.

RESULTS

The VLBW cohort had lower intelligence quotient and higher risk of significant school difficulties evaluated at age 4 and 18 years. When compared to the NBW cohort, at 30-36 years of age the VLBW cohort tended to have lower educational level, OR 1.7, 95% CI 0.8-3.9, were not financially independent OR 1.5, 95% CI 0.6-3.7, lived alone OR 2.0, 95% CI 1.0-3.8 and had higher rates of the combination of all three outcomes, OR 3.2, 95% CI 0.7-15.8.

CONCLUSIONS

We found trends towards poor socioeconomic outcomes in young adults born with VLBW. The relative disadvantages appeared smaller than that in childhood.

摘要

目的

随着早产儿存活率的大幅提高,出现了有关长期后果的问题。我们的目的是研究极低出生体重对社会经济结局的长期影响。

方法

我们对 1980 年至 1982 年在丹麦哥本哈根大学医院出生的 150 名极低出生体重儿(VLBW)进行了研究,这些婴儿此前在 2 岁、4 岁和 18 岁时接受了随访,然后与低出生体重儿、正常出生体重儿(NBW)和全国基于人群的参考队列进行了比较。我们从丹麦国家登记处获得了关于教育程度、经济独立和居住安排的数据。此外,我们还使用了以前发表的三个队列的结果。

结果

VLBW 组在 4 岁和 18 岁时的智商较低,且有较高的严重学习困难风险。与 NBW 组相比,VLBW 组在 30-36 岁时的受教育程度较低,OR 为 1.7,95%CI 为 0.8-3.9;经济上不独立的比例为 1.5,95%CI 为 0.6-3.7;独居的比例为 2.0,95%CI 为 1.0-3.8;同时具有这三种情况的比例为 3.2,95%CI 为 0.7-15.8。

结论

我们发现极低出生体重儿在成年早期存在社会经济结局不良的趋势。相对劣势似乎比在儿童时期要小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da5/10091976/2896e6487826/APA-112-78-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验