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罗马 IV 型肠易激综合征患者对药物的支付意愿。

Willingness to pay for medications among patients with Rome IV Irritable Bowel Syndrome.

机构信息

Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.

Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.

出版信息

Neurogastroenterol Motil. 2023 Feb;35(2):e14483. doi: 10.1111/nmo.14483. Epub 2022 Sep 30.

Abstract

BACKGROUND

Little is known about willingness to pay for medications among individuals with irritable bowel syndrome (IBS).

METHODS

We collected demographic, gastrointestinal symptom, psychological health, quality of life, and healthcare usage data from 752 adults with Rome IV-defined IBS. We examined willingness to pay for a hypothetical medication in return for improvement in IBS symptoms using a contingent valuation method, according to these variables.

RESULTS

The median amount of money individuals was willing to pay was £1-£50 (IQR £0-£100) per month for a medication with a 100% chance of improving IBS symptoms. Women, compared with men, (92.7% willing to pay "£0," 89.8% "£1-£50," 87.3% "£51-£100," 78.9% "£101-£200," and 78.5% "more than £200," p = 0.008) were less likely to be willing to pay for a pill with a 100% chance of improving IBS symptoms whilst those with an annual income of £30,000 or more (12.2% willing to pay "£0," 25.2% "£1-£50," 33.5% "£51-£100," 40.2% "£101-£200," and 35.1% "more than £200," p = 0.002) were more likely. We observed a higher willingness to pay among those with lower IBS-related quality of life (p = 0.002 for trend). Of all 752 individuals, 92.7%, 74.5%, and 58.0% would be willing to pay for a medication that would give them a 100%, 50%, or 30% chance of improving IBS symptoms, respectively.

CONCLUSION

Patients with IBS are willing to pay for medications which improve IBS symptoms. Future studies should investigate the relative importance of medication pricing, efficacy, and side effect profile among individuals with IBS.

摘要

背景

对于肠易激综合征(IBS)患者对药物的支付意愿知之甚少。

方法

我们从 752 名符合罗马 IV 标准的 IBS 成人患者中收集了人口统计学、胃肠道症状、心理健康、生活质量和医疗保健使用数据。我们根据这些变量使用条件价值评估法检查了对治疗 IBS 症状的假设药物的支付意愿。

结果

个人愿意每月支付的金额中位数为 1-50 英镑(IQR 0-100 英镑),以换取 IBS 症状的 100%改善。与男性相比,女性(92.7%愿意支付“0 英镑”,89.8%“1-50 英镑”,87.3%“51-100 英镑”,78.9%“101-200 英镑”和 78.5%“超过 200 英镑”,p=0.008)更不愿意支付 100%改善 IBS 症状的药物。而年收入在 30,000 英镑或以上的人(12.2%愿意支付“0 英镑”,25.2%“1-50 英镑”,33.5%“51-100 英镑”,40.2%“101-200 英镑”和 35.1%“超过 200 英镑”,p=0.002)更有可能。我们观察到较低的 IBS 相关生活质量与更高的支付意愿之间存在相关性(趋势检验 p=0.002)。在所有 752 名患者中,92.7%、74.5%和 58.0%分别愿意支付能使他们有 100%、50%或 30%改善 IBS 症状的药物。

结论

IBS 患者愿意为改善 IBS 症状的药物付费。未来的研究应该调查药物定价、疗效和副作用在 IBS 患者中的相对重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31f/10078431/790a4f06f11a/NMO-35-0-g001.jpg

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