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血气分析与中心实验室血红蛋白和电解质检测在儿科患者中的兼容性水平:单中心经验。

Compatibility levels between blood gas analysis and central laboratory hemoglobin and electrolyte tests in pediatric patients: A single-center experience.

机构信息

Department of Pediatrics, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.

Department of Biostatistics, Cukurova University, Adana, Turkey.

出版信息

Paediatr Anaesth. 2023 Feb;33(2):107-113. doi: 10.1111/pan.14567. Epub 2022 Oct 10.

Abstract

INTRODUCTION

We aimed to evaluate the interchangeability of sodium, potassium, hemoglobin, and hematocrit measurement between the blood gas analyzers and laboratory automatic analyzers results.

METHODS

This was a retrospective cross-sectional study. The results of 1927 paired samples analyzed simultaneously with the blood gas analyzer and the laboratory automatic analyzer were compared. The Bland-Altman and Cohen's kappa statistic detected the agreement between the two analyses.

RESULTS

The limits of agreement (±1.96 standard deviation of the mean difference) were -11.1 to 20.3 for sodium, -1.9 to 0.5 for potassium, -16.1 to 12.9 for hematocrit, and -5.0 to 4.0 for hemoglobin. Agreement between the two analyses was not acceptable within the defined clinically acceptable limits. In addition, none of the kappa values were higher than 0.60, which highlights the lack of agreement between the two analyzers.

CONCLUSION

The blood gas analyzers and laboratory automatic analyzers results cannot be used interchangeably.

摘要

简介

本研究旨在评估血气分析仪与实验室自动分析仪之间钠离子、钾离子、血红蛋白和血细胞比容测量结果的可互换性。

方法

这是一项回顾性的横断面研究。比较了 1927 对同时用血气分析仪和实验室自动分析仪分析的配对样本的结果。 Bland-Altman 和 Cohen's kappa 统计检测了两种分析之间的一致性。

结果

钠的一致性界限(均数差值的±1.96 标准差)为-11.1 至 20.3,钾为-1.9 至 0.5,血细胞比容为-16.1 至 12.9,血红蛋白为-5.0 至 4.0。在定义的临床可接受范围内,两种分析之间的一致性不可接受。此外,没有一个 Kappa 值高于 0.60,这表明两种分析仪之间缺乏一致性。

结论

血气分析仪和实验室自动分析仪的结果不能互换使用。

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