Richter A, Klatte D, Boran R
Z Urol Nephrol. 1987 May;80(5):263-5.
The in vivo staining of the mucosa of the bladder with methylene blue is a non-invasive, technically simple investigation not stressing for the patient by means of which it is possible to gain informations about place and extension of non-papillary plan-like growing carcinomas and severe dysplasias. Apart from this by this means a coarse estimation of the degree of malignity can be done, which in every case requires the cytologic and histopathologic control. Moreover, the already resected part of the tissue can be delimited well markedly from the parts not yet resected, since wound surfaces covered with inflammatory exudate, as they are found after the first resection, get a very intensive strong staining. The in vivo staining of the mucosa of the bladder is an essential supplementation of the formerly existing diagnostic methods in tumours of the urinary bladder.
膀胱黏膜亚甲蓝活体染色是一项非侵入性、技术操作简单的检查，不会给患者带来压力，通过该检查可以获取有关非乳头状扁平状生长癌和重度发育异常的部位及范围的信息。除此之外，通过这种方法还可以对恶性程度进行粗略估计，不过在每种情况下都需要进行细胞学和组织病理学检查。此外，已切除的组织部分能够与尚未切除的部分明显区分开来，因为首次切除后出现的覆盖有炎性渗出物的创面会呈现出非常强烈的染色。膀胱黏膜活体染色是膀胱肿瘤现有诊断方法的重要补充。
