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Gastrin in pituitary tumours.

作者信息

Bardram L, Lindholm J, Rehfeld J F

出版信息

Acta Endocrinol (Copenh). 1987 Jul;115(3):419-22. doi: 10.1530/acta.0.1150419.

DOI:10.1530/acta.0.1150419
PMID:3618087
Abstract

Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.

摘要

相似文献

1
Gastrin in pituitary tumours.
Acta Endocrinol (Copenh). 1987 Jul;115(3):419-22. doi: 10.1530/acta.0.1150419.
2
Pituitary tumors containing cholecystokinin.含有胆囊收缩素的垂体肿瘤。
N Engl J Med. 1987 May 14;316(20):1244-7. doi: 10.1056/NEJM198705143162004.
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Alpha-amidated peptides derived from pro-opiomelanocortin in human pituitary tumours.源自人垂体肿瘤中阿片促黑激素原的α-酰胺化肽。
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Peptides related to alpha-melanocyte-stimulating hormone are commonly produced by human pituitary corticotroph adenomas: no relationship with pars intermedia origin.与α-黑素细胞刺激素相关的肽通常由人垂体促肾上腺皮质激素腺瘤产生:与中间部起源无关。
J Endocrinol. 1989 Mar;120(3):531-6. doi: 10.1677/joe.0.1200531.
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The significance of elevated levels of gastrin in patients with pituitary adenoma.
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Gamma-melanotrophin-like immunoreactivities in human pituitaries, ACTH-producing pituitary adenomas, and ectopic ACTH-producing tumours: evidence for an abnormality in glycosylation in ectopic ACTH-producing tumours.
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[Morphology of the paraadenomatous adenohypophysis. A contribution to the pathogenesis of pituitary adenomas (author's transl)].[垂体腺瘤旁腺垂体的形态学。对垂体腺瘤发病机制的一项贡献(作者译)]
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Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion.
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Multiple forms of immunoreactive beta-endorphin are present in an ectopic adrenocorticotropin-producing tumor but not in normal pituitary or pituitary adenomas.多种形式的免疫反应性β-内啡肽存在于产生异位促肾上腺皮质激素的肿瘤中,但正常垂体或垂体腺瘤中不存在。
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[Immunohistochemistry of pituitary adenoma].[垂体腺瘤的免疫组织化学]
Nihon Rinsho. 1986 Mar;44(3):633-7.

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Vitamin D and its analog EB1089 induce p27 accumulation and diminish association of p27 with Skp2 independent of PTEN in pituitary corticotroph cells.维生素D及其类似物EB1089可诱导垂体促肾上腺皮质激素细胞中p27蛋白积累,并减少p27与Skp2的结合,且此过程不依赖于PTEN。
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Patterns of gastrin secretion in patients with nonfunctioning pituitary adenomas.无功能性垂体腺瘤患者的胃泌素分泌模式。
J Endocrinol Invest. 1991 Nov;14(10):861-5. doi: 10.1007/BF03347944.