Department of Dermatology, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
Department of Anatomopathology, Habib Bourguiba Hospital, Sfax, Tunisia.
Dermatol Ther. 2022 Dec;35(12):e15891. doi: 10.1111/dth.15891. Epub 2022 Oct 17.
Lichen planus (LP) is a T cell‐mediated chronic inflammatory disorder. Several clinical variants based on lesion morphology and localization are reported. LPP remains uncommon with an unknown etiology. Besides, some precipitating factors have been suggested in the literature including hepatitis C infection; restrictive underwear, localized friction, and sun exposure. Herein, we present a case of new‐onset of LPP following the ChAdOx1 nCoV‐19 (Oxford‐AstraZeneca) vaccine. A literature review was also conducted to summarize the various cases of LP induced and/or trigged by Covid‐19 vaccine.
扁平苔藓（LP）是一种 T 细胞介导的慢性炎症性疾病。据报道，有几种基于病变形态和定位的临床变异型。LPP 仍然很少见，其病因不明。此外，文献中还提出了一些诱发因素，包括丙型肝炎感染；紧身内衣、局部摩擦和阳光照射。在此，我们报告了一例接种 ChAdOx1 nCoV-19（牛津-阿斯利康）疫苗后新发 LPP 的病例。还进行了文献回顾，以总结由 Covid-19 疫苗引起和/或引发的各种 LP 病例。
