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线状苔藓样色素沉着症呈Blaschko线样分布。

Lichen planus pigmentosus in a blaschkoid distribution.

作者信息

Droms Rebecca J, Snadecki Haley, Deng April, Levin Nikki A

机构信息

University of Massachusetts Medical School, Worcester, Massachusetts.

出版信息

Dermatol Online J. 2017 Jun 15;23(6):13030/qt4fs9c744.

Abstract

Lichen planus pigmentosus is a pigmentary disorder of unknown etiology, with diffuse hyperpigmentation of sun-exposed areas, more commonly seen in some ethnic and racial groups. We report an unusual case of lichen planus pigmentosus in a 40-year-old man with Fizpatrick type III skin that was present in a blaschkoid distribution on the trunk, a distribution that has been rarely reported. This unique presentation of lichen planus pigmentosus may contribute to better understanding of the etiology, as the blaschkoid distribution may reflect underlying cutaneous mosaicism that renders those cells more susceptible to an insult that results in lichen planus pigmentosus. This disorder should be considered in the differential diagnosis of macular hyperpigmentation, especially in those from more commonly affected ethnic and racial groups, even when the distribution is atypical and in the absence of history of sun exposure.

摘要

色素性扁平苔藓是一种病因不明的色素沉着紊乱疾病,表现为暴露部位的弥漫性色素沉着,在一些种族群体中更为常见。我们报告了一例罕见的色素性扁平苔藓病例,患者为一名40岁男性,菲茨帕特里克皮肤分型为III型,其皮损呈线条状分布于躯干,这种分布此前鲜有报道。色素性扁平苔藓的这种独特表现可能有助于更好地理解其病因,因为线条状分布可能反映了潜在的皮肤嵌合体现象,使这些细胞更容易受到某种损伤,进而导致色素性扁平苔藓。在黄斑色素沉着的鉴别诊断中应考虑到这种疾病,特别是对于那些来自更易受累种族群体的患者,即使其分布不典型且无日晒史。

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