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Biomed Opt Express. 2021 May 17;12(6):3438-3449. doi: 10.1364/BOE.423741. eCollection 2021 Jun 1.
2
In vivo sensing of rabbit cornea by terahertz technology.太赫兹技术对兔眼角膜的体内探测。
J Biophotonics. 2021 Sep;14(9):e202100130. doi: 10.1002/jbio.202100130. Epub 2021 Jun 17.
3
Optical System Design for Noncontact, Normal Incidence, THz Imaging of Human Cornea.用于人眼角膜非接触、正入射太赫兹成像的光学系统设计
IEEE Trans Terahertz Sci Technol. 2018 Jan;8(1):1-12. doi: 10.1109/TTHZ.2017.2771754. Epub 2017 Nov 22.
4
THz imaging system for human cornea.用于人类角膜的太赫兹成像系统。
IEEE Trans Terahertz Sci Technol. 2018 Jan;8(1):27-37. doi: 10.1109/TTHZ.2017.2775445. Epub 2017 Dec 7.
5
Descemet Membrane Endothelial Keratoplasty: Safety and Outcomes: A Report by the American Academy of Ophthalmology.Descemet 膜内皮角膜移植术:安全性和结果:美国眼科学会报告。
Ophthalmology. 2018 Feb;125(2):295-310. doi: 10.1016/j.ophtha.2017.08.015. Epub 2017 Sep 15.
6
Outcomes of Descemet Membrane Endothelial Keratoplasty in Patients With Previous Glaucoma Surgery.既往接受青光眼手术患者的Descemet膜内皮角膜移植术的治疗效果
Cornea. 2017 Mar;36(3):284-289. doi: 10.1097/ICO.0000000000001095.
7
THz and mm-Wave Sensing of Corneal Tissue Water Content: Electromagnetic Modeling and Analysis.太赫兹和毫米波对角膜组织含水量的传感:电磁建模与分析。
IEEE Trans Terahertz Sci Technol. 2015 Mar;5(2):170-183. doi: 10.1109/TTHZ.2015.2392619.
8
THz and mm-Wave Sensing of Corneal Tissue Water Content: Sensing and Imaging Results.太赫兹和毫米波对角膜组织含水量的传感:传感与成像结果。
IEEE Trans Terahertz Sci Technol. 2015 Mar;5(2):184-196. doi: 10.1109/TTHZ.2015.2392628.
9
Tear film measurement by optical reflectometry technique.泪膜测量的光学反射测量技术。
J Biomed Opt. 2014 Feb;19(2):027001. doi: 10.1117/1.JBO.19.2.027001.
10
Graft rejection following descemet stripping automated endothelial keratoplasty: features, risk factors, and outcomes.Descemet 撕囊自动化内皮角膜移植术后排斥反应:特征、风险因素和结果。
Am J Ophthalmol. 2012 May;153(5):949-957.e1. doi: 10.1016/j.ajo.2011.10.004. Epub 2012 Jan 20.

650吉赫兹成像用于毫米波角膜反射测量法的对准验证。

650 GHz imaging as alignment verification for millimeter wave corneal reflectometry.

作者信息

Hu Yong, Baggio Mariangela, Dabironezare Shahab, Tamminen Aleksi, Toy Brandon, Ala-Laurinaho Juha, Brown Elliott, Llombart Nuria, Deng Sophie X, Wallace Vincent, Taylor Zachary D

机构信息

Department of Bioengineering, University of California, Los Angeles, CA 90095 USA.

Department of Electronics and Nanoengineering, Aalto University, Espoo, FI-02150, Finland.

出版信息

IEEE Trans Terahertz Sci Technol. 2022 Mar;12(2):151-164. doi: 10.1109/tthz.2021.3140199. Epub 2022 Jan 4.

DOI:10.1109/tthz.2021.3140199
PMID:36185397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9518788/
Abstract

A system concept for online alignment verification of millimeter-wave, corneal reflectometry is presented. The system utilizes beam scanning to generate magnitude-only reflectivity maps of the cornea at 650 GHz and compares these images to a precomputed/measured template map to confirm/reject sufficient alignment. A system utilizing 5 off-axis parabolic mirrors, a thin film beam splitter, and 2-axis galvanometric mirror was designed, simulated, and evaluated with geometric and physical optics. Simulation results informed the construction of a demonstrator system which was tested with a reference reflector. Similarity metrics computed with the aligned template and 26 misaligned positions, distributed on a 0.5 mm x 0.5 mm x 0.5 mm mesh, demonstrated sufficient misalignment detection sensitivity in 23 out of 26 positions. The results show that positional accuracy on the order of 0.5 mm is possible using 0.462 mm wavelength radiation due to the perturbation of coupling efficiency via beam distortion and beam walk-off.

摘要

本文提出了一种用于毫米波角膜反射测量在线对准验证的系统概念。该系统利用光束扫描在650GHz下生成角膜的仅幅度反射率图,并将这些图像与预先计算/测量的模板图进行比较,以确认/拒绝是否有足够的对准。设计、模拟并使用几何光学和物理光学评估了一个利用5个离轴抛物面镜、一个薄膜分束器和两轴振镜的系统。模拟结果为一个用参考反射器进行测试的演示系统的构建提供了依据。使用对齐模板和分布在0.5mm×0.5mm×0.5mm网格上的26个未对齐位置计算的相似性指标表明,在26个位置中的23个位置具有足够的未对准检测灵敏度。结果表明,由于光束畸变和光束离散导致耦合效率的扰动,使用0.462mm波长的辐射可以实现约0.5mm的位置精度。