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COVID-19 与妊娠合并感染导致胎儿死亡:病例报告。

COVID-19 and co-infection in pregnancy associated with fetal demise: a case report.

机构信息

University Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Department of Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

出版信息

Pan Afr Med J. 2022 Jul 4;42:173. doi: 10.11604/pamj.2022.42.173.33813. eCollection 2022.

DOI:10.11604/pamj.2022.42.173.33813
PMID:36187044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9482247/
Abstract

Since the global pandemic of the 2019 coronavirus disease (COVID-19), few studies have reported on the relevance of bacteria co-infection on outcome of COVID-19 patients. Little is known about the clinical presentation among pregnant women, mother-to-child transmission, and fetal outcomes. This report shows a 24-year-old nulliparous woman who was 32 weeks pregnant and was admitted to the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi Ghana with symptoms of fever (40.3°C), cough and breathlessness of two weeks duration. Her nasopharyngeal sample tested positive for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and blood culture isolated Burkholderia cepacia. She was given medications but went into pre-term labour and delivered a stillborn baby. This rare case of COVID-19 and Burkholderia cepacia co-infection emphasizes the need for a thorough assessment and appropriate treatment of patients presenting with fever and respiratory symptoms in order to mitigate poor outcome.

摘要

自 2019 年冠状病毒病(COVID-19)全球大流行以来,鲜有研究报告细菌合并感染对 COVID-19 患者结局的相关性。关于孕妇的临床表现、母婴传播和胎儿结局知之甚少。本报告介绍了一位 24 岁的初产妇,怀孕 32 周,因发热(40.3°C)、咳嗽和呼吸困难两周,入住加纳库马西夸梅·恩克鲁玛科技大学(KNUST)大学医院。她的鼻咽样本检测出严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)呈阳性,血液培养分离出洋葱伯克霍尔德菌。她接受了药物治疗,但早产并产下死胎。这例罕见的 COVID-19 和洋葱伯克霍尔德菌合并感染病例强调,需要对出现发热和呼吸道症状的患者进行彻底评估和适当治疗,以减轻不良结局。

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Cochrane Database Syst Rev. 2020 Jul 7;7(7):CD013665. doi: 10.1002/14651858.CD013665.
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Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status - United States, January 22-June 7, 2020.美国 2020 年 1 月 22 日-6 月 7 日,按妊娠状况划分的实验室确诊感染 SARS-CoV-2 的育龄期妇女特征。
MMWR Morb Mortal Wkly Rep. 2020 Jun 26;69(25):769-775. doi: 10.15585/mmwr.mm6925a1.
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