Abuarqob Sewar, Kania Brooke, Ghrewati Moutaz, Bondili Leena, Kumar Vinod, Maroules Michael
Departments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USA.
Radiol Case Rep. 2022 Sep 17;17(11):4388-4391. doi: 10.1016/j.radcr.2022.08.037. eCollection 2022 Nov.
An osteolytic lesion on imaging can be considered malignancy until proven otherwise. However, advanced stages of gout have presented with sclerotic rims and lytic lesions thought to be due to overexpression of osteoclasts. Patients have been found to demonstrate osteolytic lesions in patellar regions, which are common locations for gout to manifest; however, to our knowledge, no other cases of osteolytic gout in the acromioclavicular joint have been reported at this time. We report a rare case of a 56-year-old male who presented with acute-on-chronic left upper extremity pain and was found to have an osteolytic lesion of the shoulder on imaging. This lesion was later biopsied and found to be histologically consistent with gout. This case report aims to elucidate further understanding of the various ways that gout can present, to diagnose and treat these patients more effectively.
影像学上的溶骨性病变在未得到其他证明之前可被视为恶性病变。然而，痛风晚期出现了硬化边缘和溶骨性病变，认为这是由于破骨细胞过度表达所致。已发现患者在髌区出现溶骨性病变，这是痛风常见的表现部位；然而，据我们所知，目前尚无其他肩锁关节溶骨性痛风的病例报道。我们报告一例罕见病例，一名56岁男性，表现为慢性左上肢急性疼痛，影像学检查发现肩部有溶骨性病变。该病变后来经活检，组织学检查结果与痛风相符。本病例报告旨在进一步阐明对痛风各种表现方式的理解，以便更有效地诊断和治疗这些患者。
