Department of Ophthalmology, Government Medical College, Nagpur, Maharashtra, India.
Indian J Ophthalmol. 2022 Oct;70(10):3529-3533. doi: 10.4103/ijo.IJO_678_22.
To study the effect of intraocular lens (IOL) implantation with and without ocular viscoelastic device (OVD) on posterior capsular opacification (PCO) in eyes with phacoemulsification.
This prospective, comparative, and randomized case series included 70 patients (140 eyes) with senile cataracts scheduled for phacoemulsification and IOL implantation in a tertiary eye c are center. One eye of each patient was randomized to one of the two groups, namely, control and OVD. After phacoemulsification, the IOL was placed in the capsular bag under balanced salt solution (BSS) in the control group, whereas the IOL was placed under OVD in the OVD group. PCO was analyzed by an independent observer at 6, 12, and 18 months under slit-lamp illumination.
The mean age of the participants in the two groups was 61.2 (±9.9) years. Of the total participants, 68 (48.5%) were men and 72 (51.5%) were women. The mean keratometry (K1, K2) values of the OVD (44.26 ± 1.43, 44.93 ± 1.66) and control (44.51 ± 1.74, 44.69 ± 1.49) groups were similar. The mean IOL powers of the control and OVD groups were 21.25 (±1.94) and 21.53 (±1.86), respectively (P = 0.463). The mean best-corrected visual acuity (BCVA) of the control group at 6-, 12-, and 18-month follow-ups were 0.622 (±0.253), 0.315 (±0.203), and 0.063 (±0.163), respectively, whereas those of the OVD group were 0.592 (±0.253), 0.336 (±0.169), and 0.066 (±0.118), respectively (P = 0.922). None of the patients had postoperative raised intraocular pressure (IOP), uveitis, or endophthalmitis. Three and four eyes in the control and OVD groups, respectively, required neodymium-doped yttrium aluminum garnet (ND: YAG) capsulotomy at study termination (P = 0.999).
The hydroimplantation technique of the placement of hydrophilic IOL did not reduce the PCO rate in the 18-month follow-up period. The ND: YAG capsulotomy rate did not differ between the groups.
研究在超声乳化白内障吸除术中使用和不使用眼黏弹剂（OVD）对后囊混浊（PCO）的影响。
本前瞻性、对照、随机病例系列研究纳入了 70 名（140 只眼）计划在一家三级眼科中心行超声乳化白内障吸除术和人工晶状体植入术的老年白内障患者。每位患者的一只眼随机分为两组，即对照组和 OVD 组。在对照组中，在平衡盐溶液（BSS）下将人工晶状体植入囊袋内，而在 OVD 组中，将人工晶状体植入 OVD 下。在裂隙灯照明下，于术后 6、12 和 18 个月由独立观察者分析 PCO。
两组参与者的平均年龄为 61.2（±9.9）岁。在所有参与者中，男性 68 人（48.5%），女性 72 人（51.5%）。OVD 组（44.26±1.43，44.93±1.66）和对照组（44.51±1.74，44.69±1.49）的平均角膜曲率（K1，K2）值相似。对照组和 OVD 组的平均人工晶状体屈光度分别为 21.25（±1.94）和 21.53（±1.86）（P=0.463）。对照组在术后 6、12 和 18 个月的最佳矫正视力（BCVA）均值分别为 0.622（±0.253）、0.315（±0.203）和 0.063（±0.163），而 OVD 组的分别为 0.592（±0.253）、0.336（±0.169）和 0.066（±0.118）（P=0.922）。两组患者均无术后高眼压、葡萄膜炎或眼内炎。对照组和 OVD 组分别有 3 只和 4 只眼在研究结束时需要行钕：钇铝石榴石（ND：YAG）后囊切开术（P=0.999）。
在 18 个月的随访中，亲水人工晶状体的水植入技术并未降低 PCO 发生率。两组的 ND：YAG 后囊切开术率无差异。
