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COVID-19 后患单侧 Purtscher 样视网膜病变。

Unilateral Purtscher-like retinopathy post-COVID-19.

机构信息

Vitreoretinal Services, Shroff Eye Centre, New Delhi, India.

Retina Department Ahooja Eye and Dental Institute, Gurgaon, Haryana, India.

出版信息

Indian J Ophthalmol. 2022 Oct;70(10):3710-3712. doi: 10.4103/ijo.IJO_1486_22.

DOI:10.4103/ijo.IJO_1486_22
PMID:36190079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9789798/
Abstract

A 32-year-old male with no known systemic illness presented with unilateral Purtscher-like retinopathy in his left eye 2 weeks after recovering from a severe COVID-19 infection. Fundus examination revealed areas of intraretinal whitening and few cotton wool spots. Multimodal imaging findings were consistent with embolic occlusion of capillaries seen in Purtscher-like retinopathy. The case highlights the effect of virus-directed coagulation cascade activation leading to unilateral microvasculopathy in our patient. The case adds to the spectrum of COVID-19 retinopathy and presses that retina screening strategies should be established for patients suffering from or recovering from severe COVID-19 infection.

摘要

一位 32 岁的男性,无已知系统性疾病,在严重 COVID-19 感染康复后 2 周出现左眼单侧类似 Purtscher 的视网膜病变。眼底检查显示视网膜内有片状变白,并有少量棉絮斑。多模态成像结果与类似 Purtscher 的视网膜病变中所见的毛细血管栓塞一致。该病例突出了病毒定向凝血级联激活导致患者单侧微血管病的影响。该病例增加了 COVID-19 视网膜病变的范围,并强调应针对患有或从严重 COVID-19 感染中康复的患者制定视网膜筛查策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ec/9789798/97d4c9482f61/IJO-70-3710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ec/9789798/97d4c9482f61/IJO-70-3710-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ec/9789798/97d4c9482f61/IJO-70-3710-g001.jpg

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2
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Am J Ophthalmol Case Rep. 2021 Dec;24:101229. doi: 10.1016/j.ajoc.2021.101229. Epub 2021 Nov 11.
3
Purtscher-Like Retinopathy in a Patient with COVID-19.一名新冠肺炎患者的类Purtscher样视网膜病变
Purtscher 氏和类似 Purtscher 氏视网膜病变的病因、特征、处理和结局:168 例综合系统回顾。
PLoS One. 2024 Sep 6;19(9):e0306473. doi: 10.1371/journal.pone.0306473. eCollection 2024.
Case Rep Ophthalmol Med. 2021 Mar 20;2021:6661541. doi: 10.1155/2021/6661541. eCollection 2021.
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Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19.检测 COVID-19 患者视网膜和视神经中的 SARS-CoV-2 基因组和亚基因组 RNA。
Br J Ophthalmol. 2022 Sep;106(9):1313-1317. doi: 10.1136/bjophthalmol-2020-318618. Epub 2021 Apr 9.
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