Retina and Vitreous, Shroff Eye Centre, New Delhi, India.
Indian J Ophthalmol. 2022 Apr;70(4):1412-1415. doi: 10.4103/ijo.IJO_2837_21.
The coagulation abnormalities and thromboembolic complications of coronavirus 2 (SARS-CoV-2) are now a well-established fact. The hypercoagulable state, the tendency for thromboembolism, and a cytokine surge state have been the exclusive reasons for multiorgan failure and other morbidities that have been regularly reported in COVID-19 patients. Ocular involvement in patients with active disease and those who have recovered is uncommon but not rare. We report a case series of four patients with CRVO, BRVO, CRAO, and vitreous hemorrhage in patients with proven COVID-19 infection and no other systemic ailments. The case series also tries to correlate the elevated D-dimer values, which signify a plausible prothrombotic state with the vaso-occlusive phenomenon in the retina leading to significant visual morbidity.
新型冠状病毒（SARS-CoV-2）引起的凝血异常和血栓栓塞并发症现已得到充分证实。高凝状态、血栓栓塞倾向和细胞因子激增状态是导致多器官衰竭和其他 COVID-19 患者经常报告的并发症的唯一原因。活动期和已康复的 COVID-19 患者眼部受累并不罕见，但也不常见。我们报告了 4 例 COVID-19 感染患者的病例系列，这些患者存在视网膜中央静脉阻塞（CRVO）、视网膜分支静脉阻塞（BRVO）、前部缺血性视神经病变（CRAO）和玻璃体积血，且无其他全身疾病。该病例系列还试图将升高的 D-二聚体值与视网膜血管闭塞现象相关联，该现象提示可能存在促血栓状态，导致严重的视力损害。
