Schnitzler L, Civatte J, Robin F, Demay C
Ann Dermatol Venereol. 1987;114(4):551-6.
A progressive papular eruption on the face, limbs and vulva had been present for seven years in a 38-year old female patient. Some papules were small and confluent while others were sparse, as in nodular prurigo. Histology showed massive proliferation of the follicular sheath epithelium, connected to the lower surface of the epidermis. The lesion formed a plate-like area very similar to that observed in superficial basal cell carcinoma and corresponding to a tumour of the follicular infundibulum. Remarkable features of this case were the large number of lesions, their photosensitivity (they became pruriginous and increased in size after exposure to the sun), the presence of eccrine sweat glands beneath a skin lesion of the thigh, the basal cell degeneration of two lesions and the slight improvement observed after etretinate therapy. To our knowledge, such findings have not yet been reported in tumours of the follicular infundibulum.
一名38岁女性患者面部、四肢及外阴出现进行性丘疹疹已达七年。部分丘疹较小且融合成片,而其他则较为稀疏,类似结节性痒疹。组织学检查显示毛囊鞘上皮大量增生,与表皮下表面相连。病变形成一个板状区域,与浅表基底细胞癌中观察到的区域非常相似,对应于毛囊漏斗部肿瘤。该病例的显著特征包括大量病损、光敏性(暴露于阳光下后会变得瘙痒且增大)、大腿皮肤病变下方存在小汗腺、两个病损出现基底细胞变性以及阿维A治疗后观察到的轻微改善。据我们所知,此类发现尚未在毛囊漏斗部肿瘤中报道过。