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一名新冠康复患者出现慢性侵袭性曲霉病合并暴发性毛霉病,腭部未受累——病例报告

Chronic Invasive Aspergillosis with Fulminant Mucormycosis Sparing Palate in a Post-COVID-19 Patient - A Case Report.

作者信息

Ramani Pratibha, Krishnan Reshma Poothakulath, Pandiar Deepak, Benitha J Georgia, Ramalingam Karthikeyan, Gheena S

机构信息

Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

出版信息

Ann Maxillofac Surg. 2022 Jan-Jun;12(1):102-105. doi: 10.4103/ams.ams_296_21. Epub 2022 Aug 16.

Abstract

RATIONALE

COVID-19 patients, especially immunocompromised or severely ill, have a higher probability of suffering from invasive fungal infections.

PATIENT CONCERNS

A 41-years-old male reported with pain and heaviness in the face for the past 20 days. Patient had tested COVID-19 positive 20 days back and was recently diagnosed with diabetes mellitus. On histopathological examination numerous hyphae resembling and asper fungi were evident.

DIAGNOSIS

Chronic invasive aspergillosis with fulminant mucormycosis sparing palate.

TREATMENT

Since the lesion was spreading very rapidly the patient was referred to an isolation facility for further management.

OUTCOMES

We have postulated few hypothesis for the coinfection of aspergillosis and mucormycosis in our patient.

TAKE-AWAY LESSONS: It is important for the clinicians to systematically screen post COVID-19 patients for fungal infections, especially in immunocompromised and severely ill patients.

摘要

原理

新冠病毒病(COVID-19)患者,尤其是免疫功能低下或重症患者,患侵袭性真菌感染的可能性更高。

患者情况

一名41岁男性报告在过去20天里面部疼痛且有沉重感。该患者20天前新冠病毒检测呈阳性,最近被诊断出患有糖尿病。组织病理学检查显示有许多类似曲霉菌和毛霉菌的菌丝。

诊断

慢性侵袭性曲霉菌病伴暴发性毛霉菌病,软腭未受累。

治疗

由于病变扩散非常迅速,该患者被转至隔离设施进行进一步治疗。

结果

我们对该患者曲霉菌病和毛霉菌病合并感染提出了一些假设。

经验教训

临床医生对新冠病毒病康复患者进行真菌感染的系统筛查很重要,尤其是对免疫功能低下和重症患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3ab/9527835/1db2d774a8e1/AMS-12-102-g001.jpg

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