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护理治疗膀胱癌患者的效果:系统评价和荟萃分析。

Effects of Nursing Care for the Treatment of Patients with Bladder Cancer: A Systematic Review and Meta-analysis.

机构信息

Department of Nursing, The Second Affiliated Hospital of Nanchang University, 330029, China.

Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, 330029, China.

出版信息

Comput Math Methods Med. 2022 Sep 25;2022:9554223. doi: 10.1155/2022/9554223. eCollection 2022.

DOI:10.1155/2022/9554223
PMID:36199769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9527440/
Abstract

PURPOSE

In this study, a systematic review and meta-analysis were used to examine the effectiveness of nursing care in the treatment of bladder cancer patients. The platforms of PubMed, Embase, Cochrane Library, and Web of Science were used to conduct a thorough literature search.

METHODS

The searching approach was used to find the fundamental characteristics of 5 studies. Sample size ranged from 52 to 131,852, and total sample size was 151,166. The study was looked up in PubMed, Embase, and Web of Science, with the most recent search being done in July 2022. Utilizing a standardized form, two independent reviewers gathered pertinent information from research that qualified as literature (17). Review Manager 5.3 used the data to examine the literature. Statistics were deemed significant at < 0.05.

RESULTS

We discovered that more bladder cancer patients with T1+T2 tumor stages were receiving nursing care than those with T1+T2 tumor stages were receiving control care (mean difference =1.27, 95% CI: 1.20-1.35, < 0.00001). The proportion of bladder cancer patients with T3+T4 tumor stage in the nursing care group was lower than the proportion of patients with T3+T4 tumor stage in the control group (mean difference = 1.07; 95% CI: 1.01-1.14; < 0.00001). The difference between the number of bladder cancer patients receiving radiotherapy in the nursing care group and the control group was not statistically significant (mean difference = 1.07, 95% confidence interval [CI]: 0.99-1.16, = 0.11). There were fewer patients with bladder cancer receiving chemotherapy in the nursing care group than that in the control group (mean difference = -0.02, 95% CI: -0.0-0.02, < 0.00001). The incidence rate of patients with bladder cancer with major complications in nursing care group was lower than that of patients with bladder cancer with major complications in control group (mean difference = 0.41 95% CI: 0.18-0.93, = 0.03). When compared to patients with bladder cancer who had serious complications in the control group, the hospital death rate for nursing care patients had a greater incidence of bladder cancer patients (mean difference = 4.64 95% CI: 4.46-4.82, < 0.00001).

CONCLUSION

This study demonstrated that the effects of nursing care reduced the incidence rate of chemotherapy and the frequency of severe problems in bladder cancer patients.

摘要

目的

本研究采用系统评价和荟萃分析的方法,考察护理在膀胱癌患者治疗中的效果。使用 PubMed、Embase、Cochrane 图书馆和 Web of Science 平台进行了全面的文献检索。

方法

采用搜索方法查找 5 项研究的基本特征。样本量范围为 52 至 131852,总样本量为 151166。在 PubMed、Embase 和 Web of Science 中搜索研究,最近的一次搜索时间为 2022 年 7 月。使用标准化表格,两名独立评审员从符合文献要求的研究中收集相关信息(17)。Review Manager 5.3 用于检查文献。统计学意义的显著性水平设为 < 0.05。

结果

我们发现,接受护理的膀胱癌 T1+T2 肿瘤分期患者比接受对照护理的患者更多(平均差异=1.27,95%CI:1.20-1.35, < 0.00001)。护理组膀胱癌 T3+T4 肿瘤分期患者比例低于对照组(平均差异=1.07;95%CI:1.01-1.14; < 0.00001)。护理组和对照组接受放疗的膀胱癌患者数量差异无统计学意义(平均差异=1.07,95%置信区间[CI]:0.99-1.16,=0.11)。护理组接受化疗的膀胱癌患者人数少于对照组(平均差异=-0.02,95%CI:-0.0-0.02, < 0.00001)。护理组膀胱癌患者发生主要并发症的发生率低于对照组(平均差异=0.41,95%CI:0.18-0.93,=0.03)。与对照组膀胱癌严重并发症患者相比,护理组患者的膀胱癌死亡率更高(平均差异=4.64,95%CI:4.46-4.82, < 0.00001)。

结论

本研究表明,护理的效果降低了膀胱癌患者化疗的发生率和严重问题的发生频率。

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Retracted: Effects of Nursing Care for the Treatment of Patients with Bladder Cancer: A Systematic Review and Meta-analysis.撤回:护理对膀胱癌患者治疗的影响:一项系统评价与Meta分析。
Comput Math Methods Med. 2023 Nov 29;2023:9876720. doi: 10.1155/2023/9876720. eCollection 2023.

本文引用的文献

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PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity.PAI-1 是一种潜在的转录沉默因子,支持膀胱癌细胞的活性。
Sci Rep. 2022 Jul 16;12(1):12186. doi: 10.1038/s41598-022-16518-3.
2
Co-existence of two ciprofloxacin-resistant Salmonella enterica serovar Kentucky strains in the urine of a bladder cancer patient.一名膀胱癌患者尿液中存在两种耐环丙沙星的肠炎沙门氏菌肯塔基血清型菌株。
J Glob Antimicrob Resist. 2022 Sep;30:354-356. doi: 10.1016/j.jgar.2022.07.011. Epub 2022 Jul 14.
3
Analysis of copy number alterations in bladder cancer stem cells revealed a prognostic role of LRP1B.
分析膀胱癌干细胞的拷贝数改变揭示了 LRP1B 的预后作用。
World J Urol. 2022 Sep;40(9):2267-2273. doi: 10.1007/s00345-022-04093-1. Epub 2022 Jul 16.
4
Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis.变构激活代谢酶 GPD1 通过溶脂磷脂酸-PAFR-TRPV2 轴抑制膀胱癌生长。
J Hematol Oncol. 2022 Jul 14;15(1):93. doi: 10.1186/s13045-022-01312-5.
5
Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non-Muscle-Invasive Bladder Cancer.个体患有非肌肉浸润性膀胱癌时,其遗传种系癌症易感性基因变异。
Clin Cancer Res. 2022 Oct 3;28(19):4267-4277. doi: 10.1158/1078-0432.CCR-22-1006.
6
Effect of Radical Laparoscopic Surgery and Conventional Open Surgery on Surgical Outcomes, Complications, and Prognosis in Elderly Patients with Bladder Cancer.根治性腹腔镜手术与传统开放手术对老年膀胱癌患者手术结局、并发症及预后的影响
Evid Based Complement Alternat Med. 2022 Jul 4;2022:1681038. doi: 10.1155/2022/1681038. eCollection 2022.
7
A longitudinal single center analysis of T1HG bladder cancer: An 18 year experience.T1HG 膀胱癌的纵向单中心分析:18 年经验。
Urol Oncol. 2022 Nov;40(11):491.e1-491.e9. doi: 10.1016/j.urolonc.2022.06.007. Epub 2022 Jul 10.
8
The Effect of Narrative Nursing Intervention on Shame in Elderly Patients with Bladder Cancer after Ileal Bladder Replacement: A Cohort Study.叙事护理干预对回肠代膀胱术后老年膀胱癌患者羞耻感的影响:一项队列研究。
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