鼠伤寒沙门氏菌的hut操纵子在产气克雷伯氏菌和大肠杆菌中的表达。
Expression of the hut operons of Salmonella typhimurium in Klebsiella aerogenes and in Escherichia coli.
作者信息
Parada J L, Magasanik B
出版信息
J Bacteriol. 1975 Dec;124(3):1263-8. doi: 10.1128/jb.124.3.1263-1268.1975.
Abstract
The normal hut (histidine utilization) operons, as well as those with mutations affecting the regulation of their expression, of Salmonella typhimurium were introduced on an F' episome into cells of S. typhimurium and Klebsiella aerogenes whose chromosomal hut genes had been deleted and into cells of Escherichia coli, whose chromosome does not carry hut genes. The episomal hut operons respond in a manner very similar to induction and catabolite repression in all three organisms. The small differences found reflect both different abilities to take up inducers from the medium and different degrees of catabolite repression exerted by glucose.
摘要
将鼠伤寒沙门氏菌的正常组氨酸利用操纵子，以及那些在其表达调控方面有突变的操纵子，导入F'附加体，引入鼠伤寒沙门氏菌和产气克雷伯氏菌的细胞中，这些细胞的染色体组氨酸利用基因已被删除，还导入大肠杆菌细胞中，其染色体不携带组氨酸利用基因。附加体组氨酸利用操纵子在这三种生物体中的反应方式与诱导和分解代谢物阻遏非常相似。所发现的微小差异既反映了从培养基中摄取诱导物的不同能力，也反映了葡萄糖施加的不同程度的分解代谢物阻遏。
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