Department of Otorhinolaryngology, Hospital Clínico Universitario de Valencia, University of Valencia, Valencia, Spain.
Department of Otorhinolaryngology, Otoneurology Unit, Hospital Universitario La Fe, Valencia, Spain.
J Laryngol Otol. 2023 Jul;137(7):782-788. doi: 10.1017/S0022215122002262. Epub 2022 Oct 6.
Bilateral Ménière's disease is classified according to the time of appearance of symptoms in each ear into synchronous and metachronous types. A descriptive longitudinal study, involving 59 bilateral Ménière's disease patients, was carried out to assess the two forms of bilateral Ménière's disease.
Data on symptomatic chronology in each ear, auditory evolution and evolution of vertiginous crisis, among other aspects, were obtained, analysed and compared. Possible risk factors for Ménière's disease becoming bilateral were analysed after conducting nested case-control studies in a cohort.
The metachronous form was seen in 76.3 per cent of cases, and the time it took for the disease to become bilateral took a median time of seven years. The symptomatic triad was the most frequent symptomatic debut for the first ear in both forms. Synchronous debut presented a greater average hearing loss. Suffering from migraine and a symptomatic onset with a greater number of symptoms appear to be possible predictors of conversion to bilateral Ménière's disease.
Bilateral Ménière's disease temporal models presented differences. The study of them helps to better understand, prevent and predict the behaviour of these patients.
双侧梅尼埃病根据每侧耳症状出现的时间分为同步和不同时两种类型。对 59 例双侧梅尼埃病患者进行了描述性纵向研究,以评估两种类型的双侧梅尼埃病。
收集每侧耳症状发生的时间、听觉演变和眩晕发作演变等方面的数据,进行分析和比较。对队列中进行嵌套病例对照研究,分析双侧梅尼埃病发生的可能危险因素。
76.3%的病例为不同时发病,双侧发病的中位时间为 7 年。两种类型中,第一耳症状性三联征是最常见的首发症状。同步发病的平均听力损失更大。偏头痛和症状性发作时出现更多症状可能是双侧梅尼埃病转化的预测因素。
双侧梅尼埃病的时间模式存在差异。对它们的研究有助于更好地理解、预防和预测这些患者的病情。