Faculty of Medicine, Newfoundland and Labrador, School of Pharmacy, Memorial University of Newfoundland, Memorial University of Newfoundland, St. John's, Canada.
School of Pharmacy, Memorial University of Newfoundland, 1 - 75 Tiffany Court, St. John's, A1A 0L1, St. John's, Newfoundland and Labrador, Canada.
Int J Clin Pharm. 2022 Dec;44(6):1370-1379. doi: 10.1007/s11096-022-01419-2. Epub 2022 Oct 6.
Polypharmacy is prevalent among long-term care (LTC) residents and can cause significant morbidity. In 2018, we concluded a deprescribing pilot study that reduced potentially inappropriate medication use among LTC residents.
We sought to understand the experience and views of physicians, nurses, pharmacists, LTC residents and family members who participated in the pilot study.
Qualitative semi-structured interviews were conducted with residents and families, a physician, pharmacist and pharmacy student, and licensed-practical nurses. Interviews were audio recorded, transcribed, and analyzed using an inductive thematic analysis approach.
Interviews with 13 participants yielded themes in 3 categories: (1) views about medication use in LTC and willingness to engage in deprescribing, (2) perceived barriers and enablers for deprescribing, and (3) impact of participating in deprescribing study. Participants were willing to engage in deprescribing; residents were motivated by physician suggestions, and family members prioritized quality of life in decision-making and wanted to be part of the decision-making process. Solutions to overcome barriers included assigning responsibility to identify deprescribing opportunities to pharmacists, scheduling rounds to enable face-to-face team discussions, and consulting families to provide missing medical history to inform deprescribing decisions. Participating in a deprescribing intervention resulted in improved healthcare professional (HCP) confidence and interprofessional collaboration, and caused continued practice change after the study.
Residents, families, and HCPs are concerned about problems associated with polypharmacy in LTC and are willing to consider deprescribing. Barriers to deprescribing in LTC exist but are not insurmountable. Results provide valuable insight into strategies to optimize deprescribing interventions within LTC.
长期护理(LTC)居民普遍存在多种药物治疗,这可能导致严重的发病率。2018 年,我们完成了一项减少 LTC 居民潜在不适当药物使用的减药试验研究。
我们旨在了解参与试验研究的医生、护士、药剂师、LTC 居民及其家属的经验和观点。
对居民和家属、一名医生、一名药剂师和一名药学学生以及持照实习护士进行了定性半结构式访谈。访谈进行了录音、转录,并使用归纳主题分析方法进行了分析。
对 13 名参与者的访谈产生了 3 个类别的主题:(1)对 LTC 中药物使用的看法和参与减药的意愿,(2)减药的感知障碍和促进因素,以及(3)参与减药研究的影响。参与者愿意参与减药;居民受到医生建议的激励,家属在决策时优先考虑生活质量,并希望参与决策过程。克服障碍的解决方案包括将确定减药机会的责任分配给药剂师,安排查房以实现面对面的团队讨论,以及咨询家属以提供缺失的医疗史来为减药决策提供信息。参与减药干预措施后,医疗保健专业人员(HCP)的信心和跨专业合作得到了提高,并在研究结束后继续进行实践改变。
居民、家属和 HCP 对 LTC 中与多种药物治疗相关的问题表示关注,并愿意考虑减药。LTC 中存在减药障碍,但并非不可逾越。研究结果为优化 LTC 内减药干预措施提供了有价值的见解。